UniProt B7MDQ0
Rhomboid protease GlpG (B7MDQ0)
Rhomboid protease GlpG (UniProt B7MDQ0), EC 3.4.21.105: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- B7MDQ0
- Protein
- Rhomboid protease GlpG
- EC
- 3.4.21.105
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 3 · 1 record with a druggable one
Structures
3 records of B7MDQ0 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5MTF | A modular route to novel potent and selective inhibitors of rhomboid intramembrane proteases | x-ray diffraction | A | CL, BNG | 3 (best 0.67) |
| 5MTF | A modular route to novel potent and selective inhibitors of rhomboid intramembrane proteases | x-ray diffraction | A | W6Q, CL, BNG | — |
| B7MDQ0 | AlphaFold monomer V2.0 prediction for rhomboid protease glpg (B7MDQ0) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5MTF chain A against the predicted model B7MDQ0: TM-score 0.97, RMSD 0.86 Å
- 5MTF chain A against the predicted model B7MDQ0: TM-score 0.97, RMSD 0.86 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.