UniProt B7L0A5
Formate-tetrahydrofolate ligase (B7L0A5)
Formate-tetrahydrofolate ligase (UniProt B7L0A5), EC 6.3.4.3: 2 experimental structures and 1 predicted model on GenesisL1, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- B7L0A5
- Protein
- Formate-tetrahydrofolate ligase
- EC
- 6.3.4.3
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
3 records of B7L0A5 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7C11 | Formate--tetrahydrofolate ligase from Methylobacterium extorquens CM4 strain | x-ray diffraction | A, B, C, D, M, N, O, P | — | 20 (best 0.81) |
| 7C11 | Formate--tetrahydrofolate ligase from methylobacterium extorquens CM4 strain | x-ray diffraction | A, B, C, D, M, N, O, P | — | — |
| B7L0A5 | AlphaFold monomer V2.0 prediction for formate--tetrahydrofolate ligase (B7L0A5) | predicted | A | — | — |
Experiment against prediction
- 7C11 chain A against the predicted model B7L0A5: TM-score 1.00, RMSD 0.56 Å
- 7C11 chain A against the predicted model B7L0A5: TM-score 1.00, RMSD 0.56 Å
- 7C11 chain B against the predicted model B7L0A5: TM-score 0.99, RMSD 0.59 Å
- 7C11 chain B against the predicted model B7L0A5: TM-score 0.99, RMSD 0.59 Å
- 7C11 chain C against the predicted model B7L0A5: TM-score 1.00, RMSD 0.59 Å
- 7C11 chain C against the predicted model B7L0A5: TM-score 1.00, RMSD 0.59 Å
- 7C11 chain M against the predicted model B7L0A5: TM-score 1.00, RMSD 0.59 Å
- 7C11 chain M against the predicted model B7L0A5: TM-score 1.00, RMSD 0.59 Å
- 7C11 chain D against the predicted model B7L0A5: TM-score 1.00, RMSD 0.60 Å
- 7C11 chain D against the predicted model B7L0A5: TM-score 1.00, RMSD 0.60 Å
Elsewhere
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