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UniProt B3UES2

Envelope glycoprotein gp160 (B3UES2)

Envelope glycoprotein gp160 (UniProt B3UES2): 32 experimental structures on GenesisL1, 4 ligands bound, 198 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
B3UES2
Protein
Envelope glycoprotein gp160
Experimental structures
32
Predicted models
0
Ligands
4
Pockets
198 · 12 records with a druggable one

Structures

32 records of B3UES2 in the MolNFT archive: 32 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5VN3Cryo-EM model of B41 SOSIP.664 in complex with soluble CD4 (D1-D2) and fragment antigen binding…electron microscopyG, I, JNAG, BMA, MAN19 (best 0.75)
5VN3Cryo-EM model of B41 SOSIP.664 in complex with soluble CD4 (D1-D2) and fragment antigen binding…electron microscopyG, I, JNAG, MAN—
5VN8Cryo-EM model of B41 SOSIP.664 in complex with fragment antigen binding variable domain of b12electron microscopyG, D, ENAG, BMA, MAN19 (best 0.80)
5VN8Cryo-EM model of B41 SOSIP.664 in complex with fragment antigen binding variable domain of B12electron microscopyG, D, ENAG, MAN—
6CH9Crystal structure of a natively-glycosylated B41 SOSIP.664 HIV-1 Envelope Trimer in complex with…x-ray diffractionGNAG, BMA, MAN9 (best 0.83)
6CH9Crystal structure of a natively-glycosylated B41 SOSIP.664 HIV-1 envelope trimer in complex with…x-ray diffractionGNAG, MAN—
6EDUB41 SOSIP.664 in complex with soluble CD4 (D1-D2), the co-receptor mimicking antibody 21c and the…electron microscopyD, E, FNAG, MAN17 (best 0.80)
6EDUB41 SOSIP.664 in complex with soluble CD4 (D1-D2), the co-receptor mimicking antibody 21C and the…electron microscopyD, E, FNAG, MAN—
6MCOCrystal structure of the B41 SOSIP.664 Env trimer with PGT124 and 35O22 Fabs, in P23 space groupx-ray diffractionGNAG, MAN13 (best 0.65)
6MCOCrystal structure of the B41 SOSIP.664 env trimer with PGT124 and 35O22 fabs, in P23 space groupx-ray diffractionGNAG—
6MDTCrystal structure of the B41 SOSIP.664 Env trimer with PGT124 and 35O22 Fabs, in P63 space groupx-ray diffractionBNAG5 (best 0.62)
6MDTCrystal structure of the B41 SOSIP.664 env trimer with PGT124 and 35O22 fabs, in P63 space groupx-ray diffractionBNAG—
6MUFCrystal Structure of HIV-1 B41 SOSIP.664 Prefusion Env Trimer in Complex with Human Antibodies…x-ray diffractionGNAG—
6MUFCrystal structure of HIV-1 B41 SOSIP.664 prefusion env trimer in complex with human antibodies…x-ray diffractionGNAG—
6MUGCrystal Structure of HIV-1 B41 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry…x-ray diffractionGNAG, JYS—
6MUGCrystal structure of HIV-1 B41 SOSIP.664 prefusion env trimer bound to small molecule HIV-1 entry…x-ray diffractionGNAG, JYS—
6OKPB41 SOSIP.664 in complex with the silent-face antibody SF12 and V3-targeting antibody 10-1074electron microscopyD, E, FNAG, MAN, BMA19 (best 0.81)
6OKPB41 SOSIP.664 in complex with the silent-face antibody SF12 and V3- targeting antibody 10-1074electron microscopyD, E, FNAG, MAN, BMA—
6OPNCD4- and 17-bound HIV-1 Env B41 SOSIP in complex with small molecule GO35electron microscopyA, D, GNAG, MAN19 (best 0.77)
6OPNCD4- and 17-bound HIV-1 env B41 sosip in complex with small molecule GO35electron microscopyA, D, GNAG, MAN—
6OPOSymmetric model of CD4- and 17-bound B41 HIV-1 env sosip in complex with ddmelectron microscopyA, D, JNAG, MAN—
6OPPAsymmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with DDMelectron microscopyA, D, JNAG, MAN, BMA19 (best 0.75)
6OPPAsymmetric model of CD4- and 17-bound B41 HIV-1 env sosip in complex with ddmelectron microscopyA, D, JNAG, MAN, BMA—
6OPQCD4- and 17-bound HIV-1 Env B41 SOSIP frozen with LMNGelectron microscopyA, D, ENAG, MAN20 (best 0.80)
6OPQCD4- and 17-bound HIV-1 env B41 sosip frozen with lmngelectron microscopyA, D, ENAG, MAN—
6U59HIV-1 B41 SOSIP.664 in complex with rabbit antibody 13Belectron microscopyA, C, GNAG, MAN20 (best 0.86)
6U59HIV-1 B41 SOSIP.664 in complex with rabbit antibody 13Belectron microscopyA, C, GNAG, MAN—
6X5BSymmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with small molecule GO52electron microscopyA, D, JNAG, MAN19 (best 0.82)
6X5BSymmetric model of CD4- and 17-bound B41 HIV-1 env sosip in complex with small molecule GO52electron microscopyA, D, JNAG, MAN—
6X5CAsymmetric model of CD4-bound B41 HIV-1 Env SOSIP in complex with small molecule GO52electron microscopyA, D, ENAG, MAN—
6X5CAsymmetric model of CD4-bound B41 HIV-1 env sosip in complex with small molecule GO52electron microscopyA, D, ENAG, MAN—
8D5Canti-HIV-1 gp120-sCD4 complex antibody CG10 Fab in complex with B41-sCD4electron microscopyA, B, C——

Ligands

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 31 records
  • MAN · alpha-D-mannopyranose · in 24 records
  • BMA · beta-D-mannopyranose · in 7 records
  • JYS · 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-(4-bromo-7-fluoro-1H-indol-3-yl)ethane-1,2-dione · in 2 records

Elsewhere

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