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UniProt B1AKP8

non-specific serine/threonine protein kinase (B1AKP8)

non-specific serine/threonine protein kinase (UniProt B1AKP8), EC 2.7.11.1: 2 experimental structures on GenesisL1, 3 ligands bound, 11 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
B1AKP8
Protein
non-specific serine/threonine protein kinase
EC
2.7.11.1
Experimental structures
2
Predicted models
0
Ligands
3
Pockets
11 · 2 records with a druggable one

Structures

2 records of B1AKP8 in the MolNFT archive: 2 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8ER6FKBP12-FRB in Complex with Compound 11x-ray diffractionB, D, FXYU6 (best 0.77)
8ER7FKBP12-FRB in Complex with Compound 12x-ray diffractionB, D, FXZ3, CL5 (best 0.79)

Ligands

  • CL · Chloride ion · in 1 record
  • XYU · (3S,5R,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-5,9,27-trihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-5,6,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-octadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,11,28,29(4H,31H)-tetrone · in 1 record
  • XZ3 · (3S,5R,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-5,10,21-trimethoxy-6,8,12,14,20,26-hexamethyl-5,6,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-octadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,11,28,29(4H,31H)-tetrone · in 1 record

Elsewhere

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