UniProt A9BGZ9
L-lactate dehydrogenase (A9BGZ9)
L-lactate dehydrogenase (UniProt A9BGZ9), EC 1.1.1.27: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- A9BGZ9
- Protein
- L-lactate dehydrogenase
- EC
- 1.1.1.27
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 2 records with a druggable one
Structures
3 records of A9BGZ9 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6H9S | Crystal dimeric structure of Petrotoga mobilis lactate dehydrogenase with NADH | x-ray diffraction | A, B | NAD | 6 (best 0.73) |
| 6H9S | Crystal dimeric structure of petrotoga mobilis lactate dehydrogenase with NADH | x-ray diffraction | A, B | NAD | — |
| A9BGZ9 | AlphaFold monomer V2.0 prediction for L-lactate dehydrogenase (A9BGZ9) | predicted | A | — | 2 (best 0.72) |
Ligands
- NAD · Nicotinamide-adenine-dinucleotide · in 2 records
Experiment against prediction
- 6H9S chain A against the predicted model A9BGZ9: TM-score 0.98, RMSD 0.93 Å
- 6H9S chain A against the predicted model A9BGZ9: TM-score 0.98, RMSD 0.93 Å
- 6H9S chain B against the predicted model A9BGZ9: TM-score 0.98, RMSD 0.95 Å
- 6H9S chain B against the predicted model A9BGZ9: TM-score 0.98, RMSD 0.95 Å
Elsewhere
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