UniProt A8WEZ7
4Fe-4S cluster-binding domain-containing protein (A8WEZ7)
4Fe-4S cluster-binding domain-containing protein (UniProt A8WEZ7): 3 experimental structures on GenesisL1, 7 ligands bound, 21 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A8WEZ7
- Protein
- 4Fe-4S cluster-binding domain-containing protein
- Experimental structures
- 3
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 21 · 3 records with a druggable one
Structures
3 records of A8WEZ7 in the MolNFT archive: 3 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7WZV | The structure of a Twitch Radical SAM Dehydrogenase SpeY | x-ray diffraction | A, B | SF4, SAM, 7P8, SO4, NA, CL | 6 (best 0.81) |
| 7WZX | The structure of a Twitch Radical SAM Dehydrogenase SpeY | x-ray diffraction | A | SF4, SAM, 7PK, SO4 | 5 (best 0.80) |
| 7X0B | The structure of a Twitch Radical SAM Dehydrogenase SpeY | x-ray diffraction | A, B | SF4, SAM, CL, SO4, NA | 10 (best 0.81) |
Ligands
- SAM · S-adenosylmethionine · in 3 records
- SF4 · Iron/sulfur cluster · in 3 records
- SO4 · Sulfate ion · in 3 records
- CL · Chloride ion · in 2 records
- NA · Sodium ion · in 2 records
- 7P8 · (1~{S},2~{R},4~{S},5~{R})-2,4-bis(methylamino)-6-[(2~{S},3~{R},4~{S},6~{R})-6-methyl-3,4-bis(oxidanyl)oxan-2-yl]oxy-cyclohexane-1,3,5-triol · in 1 record
- 7PK · (2~{S},4~{S},6~{R})-2-[(2~{S},3~{R},5~{S},6~{R})-3,5-bis(methylamino)-2,4,6-tris(oxidanyl)cyclohexyl]oxy-6-methyl-4-oxidanyl-oxan-3-one · in 1 record
Elsewhere
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