UniProt A8MW95
Beclin-2 (A8MW95)
Beclin-2 (UniProt A8MW95): 5 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- A8MW95
- Protein
- Beclin-2
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 13 · 2 records with a druggable one
Structures
6 records of A8MW95 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5K7B | Beclin 2 CCD homodimer | x-ray diffraction | A, B, C, D | — | 6 (best 0.61) |
| 5K7B | Beclin 2 ccd homodimer | x-ray diffraction | A, B, C, D | — | — |
| 5K9L | Beclin 2 CCD N187L mutant homodimer | x-ray diffraction | A, B, C, D | — | 6 (best 0.60) |
| 5K9L | Beclin 2 ccd N187L mutant homodimer | x-ray diffraction | A, B, C, D | — | — |
| 8GU7 | Selective targeting of the Beclin 2-Atg14L coiled coil complex by stapled peptides promotes… | x-ray diffraction | C, D | — | 1 (best 0.31) |
| A8MW95 | AlphaFold monomer V2.0 prediction for beclin-2 (A8MW95) | predicted | A | — | — |
Experiment against prediction
- 8GU7 chain C against the predicted model A8MW95: TM-score 0.93, RMSD 0.52 Å
- 5K7B chain A against the predicted model A8MW95: TM-score 0.90, RMSD 1.16 Å
- 5K7B chain A against the predicted model A8MW95: TM-score 0.90, RMSD 1.16 Å
- 5K9L chain C against the predicted model A8MW95: TM-score 0.89, RMSD 1.26 Å
- 5K9L chain C against the predicted model A8MW95: TM-score 0.89, RMSD 1.26 Å
- 8GU7 chain D against the predicted model A8MW95: TM-score 0.89, RMSD 0.58 Å
- 5K7B chain D against the predicted model A8MW95: TM-score 0.88, RMSD 1.40 Å
- 5K7B chain D against the predicted model A8MW95: TM-score 0.88, RMSD 1.40 Å
- 5K9L chain D against the predicted model A8MW95: TM-score 0.88, RMSD 1.71 Å
- 5K9L chain D against the predicted model A8MW95: TM-score 0.88, RMSD 1.71 Å
Elsewhere
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