UniProt A8MW92
PHD finger protein 20-like protein 1 (A8MW92)
PHD finger protein 20-like protein 1 (UniProt A8MW92): 12 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- A8MW92
- Protein
- PHD finger protein 20-like protein 1
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 16 · 3 records with a druggable one
Structures
13 records of A8MW92 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6L0X | The First Tudor Domain of PHF20L1 | x-ray diffraction | A, B | — | 1 (best 0.58) |
| 6L0X | The first tudor domain of PHF20L1 | x-ray diffraction | A, B | — | — |
| 6L10 | PHF20L1 Tudor1 - MES | x-ray diffraction | A, B, C, D | SO4 | 5 (best 0.61) |
| 6L10 | PHF20L1 TUDOR1 - mes | x-ray diffraction | A, B, C, D | SO4 | — |
| 6L1C | Crystal Structure Of of PHF20L1 Tudor1 Y24L mutant | x-ray diffraction | A | SO4 | — |
| 6L1C | Crystal structure of of PHF20L1 TUDOR1 Y24L mutant | x-ray diffraction | A | SO4 | — |
| 6L1F | Crystal structure of PHF20L1 Tudor1 in complex with K142me1 DNMT1 | x-ray diffraction | B | — | — |
| 6L1F | Crystal structure of PHF20L1 TUDOR1 in complex with K142ME1 DNMT1 | x-ray diffraction | B | — | — |
| 6L1I | Crystal Structure Of of PHF20L1 Tudor1 Y24W/Y29W mutant | x-ray diffraction | B | SO4 | — |
| 6L1I | Crystal structure of of PHF20L1 TUDOR1 Y24W/Y29W mutant | x-ray diffraction | B | SO4 | — |
| 6L1P | Crystal structure of PHF20L1 in complex with Hit 1 | x-ray diffraction | B, A, C, D | E3X, SO4 | 6 (best 0.68) |
| 6L1P | Crystal structure of PHF20L1 in complex with hit 1 | x-ray diffraction | B, A, C, D | E3X, SO4 | — |
| A8MW92 | AlphaFold monomer V2.0 prediction for phd finger protein 20-like protein 1 (A8MW92) | predicted | A | — | 4 (best 0.45) |
Ligands
Experiment against prediction
- 6L1C chain A against the predicted model A8MW92: TM-score 0.98, RMSD 0.47 Å
- 6L1C chain A against the predicted model A8MW92: TM-score 0.98, RMSD 0.47 Å
- 6L1F chain B against the predicted model A8MW92: TM-score 0.96, RMSD 0.62 Å
- 6L1F chain B against the predicted model A8MW92: TM-score 0.96, RMSD 0.62 Å
- 6L0X chain A against the predicted model A8MW92: TM-score 0.95, RMSD 0.70 Å
- 6L0X chain A against the predicted model A8MW92: TM-score 0.95, RMSD 0.70 Å
- 6L1P chain A against the predicted model A8MW92: TM-score 0.95, RMSD 0.80 Å
- 6L1P chain A against the predicted model A8MW92: TM-score 0.95, RMSD 0.80 Å
- 6L10 chain D against the predicted model A8MW92: TM-score 0.94, RMSD 0.82 Å
- 6L10 chain D against the predicted model A8MW92: TM-score 0.94, RMSD 0.82 Å
Elsewhere
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