UniProt A8MT69
Centromere protein X (A8MT69)
Centromere protein X (UniProt A8MT69): 22 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- A8MT69
- Protein
- Centromere protein X
- Experimental structures
- 22
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
23 records of A8MT69 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4DRA | Crystal structure of MHF complex | x-ray diffraction | E, F, G, H | — | — |
| 4DRA | Crystal structure of mhf complex | x-ray diffraction | E, F, G, H | — | — |
| 4DRB | The crystal structure of FANCM bound MHF complex | x-ray diffraction | J, K, L, M, N, O | — | — |
| 4DRB | The crystal structure of fancm bound mhf complex | x-ray diffraction | J, K, L, M, N, O | — | — |
| 4E44 | Crystal structure of the hMHF1/hMHF2 Histone-Fold Tetramer | x-ray diffraction | B, D | — | — |
| 4E44 | Crystal structure of the HMHF1/HMHF2 histone-fold tetramer | x-ray diffraction | B, D | — | — |
| 4E45 | Crystal structure of the hMHF1/hMHF2 Histone-Fold Tetramer in Complex with Fanconi Anemia… | x-ray diffraction | B, D, G, I, L, N | — | — |
| 4E45 | Crystal structure of the HMHF1/HMHF2 histone-fold tetramer in complex with fanconi anemia… | x-ray diffraction | B, D, G, I, L, N | — | — |
| 4NDY | Human MHF1-MHF2 DNA complex | x-ray diffraction | D, H, B, L, M, N, U, V, W, X | — | — |
| 4NDY | Human MHF1-MHF2 DNA complex | x-ray diffraction | D, H, B, L, M, N, U, V, W, X | — | — |
| 4NE1 | Human MHF1 MHF2 DNA complexes | x-ray diffraction | D, H, B, L, M, N, U, V, W, X, Z, b, d, h, i, j, o, p, q, r | — | — |
| 4NE1 | Human MHF1 MHF2 DNA complexes | x-ray diffraction | D, H, B, L, M, N, U, V, W, X, Z, b, d, h, i, j, o, p, q, r | — | — |
| 4NE3 | Human MHF1-MHF2 complex | x-ray diffraction | B | — | — |
| 4NE3 | Human MHF1-MHF2 complex | x-ray diffraction | B | — | — |
| 4NE5 | Human MHF1-MHF2 complex | x-ray diffraction | B, D, F, H | — | — |
| 4NE5 | Human MHF1-MHF2 complex | x-ray diffraction | B, D, F, H | — | — |
| 4NE6 | Human MHF1-MHF2 complex | x-ray diffraction | B, D | — | — |
| 4NE6 | Human MHF1-MHF2 complex | x-ray diffraction | B, D | — | — |
| 7R5S | Structure of the human ccan bound to alpha satellite DNA | electron microscopy | X | — | — |
| 7XHN | Structure of human inner kinetochore CCAN-DNA complex | electron microscopy | X | — | 2 (best 0.75) |
| 7YWX | Structure of the human CCAN CENP-A alpha-satellite complex | electron microscopy | X | — | — |
| 7YWX | Structure of the human ccan cenp-a alpha-satellite complex | electron microscopy | X | — | — |
| A8MT69 | AlphaFold monomer V2.0 prediction for centromere protein X (A8MT69) | predicted | A | — | — |
Experiment against prediction
- 4NE5 chain D against the predicted model A8MT69: TM-score 0.99, RMSD 0.28 Å
- 4NE5 chain D against the predicted model A8MT69: TM-score 0.99, RMSD 0.28 Å
- 4NE5 chain B against the predicted model A8MT69: TM-score 0.99, RMSD 0.29 Å
- 4NE5 chain B against the predicted model A8MT69: TM-score 0.99, RMSD 0.29 Å
- 4NE5 chain H against the predicted model A8MT69: TM-score 0.99, RMSD 0.29 Å
- 4NE5 chain H against the predicted model A8MT69: TM-score 0.99, RMSD 0.29 Å
- 4NE5 chain F against the predicted model A8MT69: TM-score 0.99, RMSD 0.29 Å
- 4NE5 chain F against the predicted model A8MT69: TM-score 0.99, RMSD 0.29 Å
- 4DRA chain E against the predicted model A8MT69: TM-score 0.99, RMSD 0.30 Å
- 4DRA chain E against the predicted model A8MT69: TM-score 0.99, RMSD 0.30 Å
Elsewhere
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