UniProt A6ZR80
Ribosome biogenesis protein NSA2 (A6ZR80)
Ribosome biogenesis protein NSA2 (UniProt A6ZR80): 9 experimental structures and 1 predicted model on GenesisL1, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- A6ZR80
- Protein
- Ribosome biogenesis protein NSA2
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 11 · 7 records with a druggable one
Structures
10 records of A6ZR80 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6ELZ | State E (TAP-Flag-Ytm1 E80A) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | electron microscopy | r | — | — |
| 6YLG | Rix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement) | electron microscopy | r | — | 2 (best 0.87) |
| 6YLH | Rix1-Rea1 pre-60S particle - full composite structure | electron microscopy | r | — | 3 (best 0.88) |
| 6YLX | pre-60S State NE1 (TAP-Flag-Nop53) | electron microscopy | r | — | 1 (best 0.84) |
| 6YLY | pre-60S State NE2 (TAP-Flag-Nop53) | electron microscopy | r | — | 1 (best 0.89) |
| 7NAC | State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model | electron microscopy | r | — | — |
| 7R6K | State E2 nucleolar 60S ribosomal intermediate - Model for Noc2/Noc3 region | electron microscopy | r | — | 1 (best 0.81) |
| 7R7A | State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model | electron microscopy | r | — | 1 (best 0.86) |
| 7U0H | State NE1 nucleolar 60S ribosome biogenesis intermediate - Overall model | electron microscopy | r | — | 1 (best 0.84) |
| A6ZR80 | AlphaFold monomer V2.0 prediction for ribosome biogenesis protein NSA2 (A6ZR80) | predicted | A | — | 1 (best 0.25) |
Experiment against prediction
- 6YLY chain r against the predicted model A6ZR80: TM-score 0.83, RMSD 1.90 Å
- 6YLG chain r against the predicted model A6ZR80: TM-score 0.62, RMSD 1.05 Å
- 6YLH chain r against the predicted model A6ZR80: TM-score 0.62, RMSD 1.05 Å
- 6YLX chain r against the predicted model A6ZR80: TM-score 0.54, RMSD 2.47 Å
- 7R7A chain r against the predicted model A6ZR80: TM-score 0.54, RMSD 2.01 Å
- 7NAC chain r against the predicted model A6ZR80: TM-score 0.54, RMSD 1.78 Å
- 6ELZ chain r against the predicted model A6ZR80: TM-score 0.54, RMSD 1.78 Å
- 7U0H chain r against the predicted model A6ZR80: TM-score 0.53, RMSD 1.31 Å
- 7R6K chain r against the predicted model A6ZR80: TM-score 0.27, RMSD 1.54 Å
Elsewhere
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