UniProt A6ZNQ1

ATP-dependent RNA helicase DBP5 (A6ZNQ1)

ATP-dependent RNA helicase DBP5 (UniProt A6ZNQ1), EC 3.6.4.13: 2 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…

UniProt: A6ZNQ1
Protein: ATP-dependent RNA helicase DBP5
EC: 3.6.4.13
Experimental structures: 2
Predicted models: 1
Ligands: 4
Pockets: 4 · 1 record with a druggable one

Structures

3 records of A6ZNQ1 in the MolNFT archive: 2 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
5ELX	S. cerevisiae Dbp5 bound to RNA and mant-ADP BeF3	x-ray diffraction	A	M2A, MG, BEF, NO3	4 (best 0.62)
5ELX	S. cerevisiae DBP5 bound to RNA and mant-ADP BEF3	x-ray diffraction	A	—	—
A6ZNQ1	AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase DBP5 (A6ZNQ1)	predicted	A	—	—

Ligands

BEF · Beryllium trifluoride ion · in 1 record
M2A · [(2~{R},3~{R},4~{R},5~{S})-2-(6-aminopurin-9-yl)-4-oxidanyl-5-[[oxidanyl(phosphonooxy)phosphoryl]oxymethyl]oxolan-3-yl] 2-(methylamino)benzoate · in 1 record
MG · Magnesium ion · in 1 record
NO3 · Nitrate ion · in 1 record

Experiment against prediction

5ELX chain A against the predicted model A6ZNQ1: TM-score 0.99, RMSD 0.81 Å
5ELX chain A against the predicted model A6ZNQ1: TM-score 0.99, RMSD 0.81 Å

Elsewhere

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