UniProt A6ZLG6
Structure-specific endonuclease subunit SLX1 (A6ZLG6)
Structure-specific endonuclease subunit SLX1 (UniProt A6ZLG6), EC 3.1.-.-: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 24 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- A6ZLG6
- Protein
- Structure-specific endonuclease subunit SLX1
- EC
- 3.1.-.-
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 24 · 4 records with a druggable one
Structures
7 records of A6ZLG6 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7CQ2 | Crystal structure of Slx1-Slx4 | x-ray diffraction | A, B | ZN | 10 (best 0.56) |
| 7CQ2 | Crystal structure of SLX1-SLX4 | x-ray diffraction | A, B | ZN | — |
| 7CQ3 | Crystal structure of Slx1-Slx4 | x-ray diffraction | A | ZN, SO4 | 6 (best 0.52) |
| 7CQ3 | Crystal structure of SLX1-SLX4 | x-ray diffraction | A | ZN, SO4 | — |
| 7CQ4 | Crystal structure of Slx1-Slx4 in complex with 5'flap DNA | x-ray diffraction | A | ZN | 4 (best 0.71) |
| 7CQ4 | Crystal structure of SLX1-SLX4 in complex with 5'FLAP DNA | x-ray diffraction | A | ZN | — |
| A6ZLG6 | AlphaFold monomer V2.0 prediction for structure-specific endonuclease subunit SLX1 (A6ZLG6) | predicted | A | — | 4 (best 0.57) |
Ligands
Experiment against prediction
- 7CQ3 chain A against the predicted model A6ZLG6: TM-score 0.95, RMSD 1.60 Å
- 7CQ3 chain A against the predicted model A6ZLG6: TM-score 0.95, RMSD 1.60 Å
- 7CQ2 chain B against the predicted model A6ZLG6: TM-score 0.95, RMSD 1.75 Å
- 7CQ2 chain B against the predicted model A6ZLG6: TM-score 0.95, RMSD 1.75 Å
- 7CQ4 chain A against the predicted model A6ZLG6: TM-score 0.94, RMSD 1.70 Å
- 7CQ4 chain A against the predicted model A6ZLG6: TM-score 0.94, RMSD 1.70 Å
- 7CQ2 chain A against the predicted model A6ZLG6: TM-score 0.94, RMSD 1.56 Å
- 7CQ2 chain A against the predicted model A6ZLG6: TM-score 0.94, RMSD 1.56 Å
Elsewhere
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