UniProt A6VD57

RNA-binding protein Hfq (A6VD57)

RNA-binding protein Hfq (UniProt A6VD57): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: A6VD57
Protein: RNA-binding protein Hfq
Experimental structures: 4
Predicted models: 1
Ligands: 1
Pockets: 19 · 1 record with a druggable one

Structures

5 records of A6VD57 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
5I21	Y55W Hfq from Pseudomonas aeruginosa	x-ray diffraction	A, B, C	CL	—
5I21	Y55W hfq from pseudomonas aeruginosa	x-ray diffraction	A, B, C	CL	—
6XYJ	Hfq from E.coli with inserted long loop L4 sequence	x-ray diffraction	AAA, BBB, CCC, DDD, EEE, FFF	—	—
8BVJ	Hfq-Crc-estA translation repression complex	electron microscopy	R, T, J, L, N, P, X, Y, S, U, V, W, K, M, D, E, F, I	—	19 (best 0.79)
A6VD57	AlphaFold monomer V2.0 prediction for RNA-binding protein hfq (A6VD57)	predicted	A	—	—

Ligands

CL · Chloride ion · in 2 records

Experiment against prediction

5I21 chain B against the predicted model A6VD57: TM-score 0.99, RMSD 0.35 Å
5I21 chain B against the predicted model A6VD57: TM-score 0.99, RMSD 0.35 Å
5I21 chain C against the predicted model A6VD57: TM-score 0.98, RMSD 0.38 Å
5I21 chain A against the predicted model A6VD57: TM-score 0.98, RMSD 0.38 Å
5I21 chain A against the predicted model A6VD57: TM-score 0.98, RMSD 0.38 Å
8BVJ chain S against the predicted model A6VD57: TM-score 0.96, RMSD 0.59 Å
8BVJ chain I against the predicted model A6VD57: TM-score 0.96, RMSD 0.60 Å
8BVJ chain D against the predicted model A6VD57: TM-score 0.95, RMSD 0.66 Å
8BVJ chain U against the predicted model A6VD57: TM-score 0.95, RMSD 0.63 Å
8BVJ chain K against the predicted model A6VD57: TM-score 0.95, RMSD 0.75 Å

Elsewhere

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