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UniProt A6NNK5

TP53-binding protein 1 (A6NNK5)

TP53-binding protein 1 (UniProt A6NNK5): 10 experimental structures on GenesisL1, 3 ligands bound, 10 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A6NNK5
Protein
TP53-binding protein 1
Experimental structures
10
Predicted models
0
Ligands
3
Pockets
10 · 3 records with a druggable one

Structures

10 records of A6NNK5 in the MolNFT archive: 10 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6UPTTudor Domain of Tumor suppressor p53BP1 with MFP-2706x-ray diffractionA, BQFM, UNX1 (best 0.41)
6UPTTudor domain of tumor suppressor P53BP1 with mfp-2706x-ray diffractionA, BQFM, UNX—
7YQKcryo-EM structure of gammaH2AXK15ub-H4K20me2 nucleosome bound to 53BP1electron microscopyN—1 (best 0.68)
7YQKCryo-EM structure of GAMMAH2AXK15UB-H4K20ME2 nucleosome bound to 53BP1electron microscopyN——
8SVGUbiquitin variant i53 in complex with 53BP1 Tudor domainx-ray diffractionA——
8SVHUbiquitin variant i53 mutant L67R bound to 53BP1 Tudor Domainx-ray diffractionA—1 (best 0.38)
8SVIUbiquitin variant i53:Mutant L67H with 53BP1 Tudor domainx-ray diffractionA—1 (best 0.39)
8SVJUbiquitin variant i53: mutant VHH with 53BP1 Tudor domainx-ray diffractionA—1 (best 0.52)
8T2DUbiquitin variant i53:Mutant T12Y.T14E.L67R with 53BP1 Tudor domainx-ray diffractionA—1 (best 0.24)
9CKJCo-crystal structure of 53BP1 tandem Tudor domains in complex with UNC9512x-ray diffractionA, B, C, D, E, FA1AY8, UNX4 (best 0.79)

Ligands

  • UNX · Unknown atom or ion · in 3 records
  • QFM · 2-((2-chlorobenzyl)thio)-4,5-dihydro-1H-imidazole · in 2 records
  • A1AY8 · (3S)-1-[4-(4-methylpiperazin-1-yl)pyridine-2-carbonyl]-N-[(3M)-3-(3-oxo-2,3-dihydro-1H-isoindol-5-yl)phenyl]piperidine-3-carboxamide · in 1 record

Elsewhere

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