UniProt A6H8Y1

Transcription factor TFIIIB component B'' homolog (A6H8Y1)

Transcription factor TFIIIB component B'' homolog (UniProt A6H8Y1): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 14 pockets. Binding sites, druggability and experiment against prediction…

UniProt: A6H8Y1
Protein: Transcription factor TFIIIB component B'' homolog
Experimental structures: 5
Predicted models: 1
Ligands: 1
Pockets: 14 · 4 records with a druggable one

Structures

6 records of A6H8Y1 in the MolNFT archive: 5 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
5N9G	TFIIIB -TBP/Brf2/DNA and SANT domain of Bdp1-	x-ray diffraction	C, H	NA	9 (best 0.75)
5N9G	Tfiiib -TBP/BRF2/DNA and sant domain of BDP1-	x-ray diffraction	C, H	NA	—
8ITY	human RNA polymerase III pre-initiation complex closed DNA 1	electron microscopy	W	—	2 (best 0.79)
8IUE	RNA polymerase III pre-initiation complex melting complex 1	electron microscopy	W	—	2 (best 0.81)
8IUH	RNA polymerase III pre-initiation complex open complex 1	electron microscopy	W	—	1 (best 0.76)
A6H8Y1	AlphaFold monomer V2.0 prediction for transcription factor tfiiib component B'' homolog (A6H8Y1)	predicted	A	—	—

Ligands

NA · Sodium ion · in 2 records

Experiment against prediction

5N9G chain H against the predicted model A6H8Y1: TM-score 0.92, RMSD 1.31 Å
5N9G chain H against the predicted model A6H8Y1: TM-score 0.92, RMSD 1.31 Å
5N9G chain C against the predicted model A6H8Y1: TM-score 0.89, RMSD 1.73 Å
5N9G chain C against the predicted model A6H8Y1: TM-score 0.89, RMSD 1.73 Å
8ITY chain W against the predicted model A6H8Y1: TM-score 0.79, RMSD 2.37 Å
8IUH chain W against the predicted model A6H8Y1: TM-score 0.76, RMSD 2.27 Å
8IUE chain W against the predicted model A6H8Y1: TM-score 0.76, RMSD 2.29 Å

Elsewhere

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