UniProt A5U1E6
Fructose-1,6-bisphosphatase class 2 (A5U1E6)
Fructose-1,6-bisphosphatase class 2 (UniProt A5U1E6), EC 3.1.3.11: 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- A5U1E6
- Protein
- Fructose-1,6-bisphosphatase class 2
- EC
- 3.1.3.11
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 18 · 2 records with a druggable one
Structures
4 records of A5U1E6 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6AYU | Crystal structure of fructose-1,6-bisphosphatase T84S from Mycobacterium tuberculosis | x-ray diffraction | A, B | F6P, MG | 8 (best 0.81) |
| 6AYU | Crystal structure of fructose-1,6-bisphosphatase T84S from mycobacterium tuberculosis | x-ray diffraction | A, B | F6P, MG | — |
| 7TXB | Structure of the Class II Fructose-1,6-Bisphophatase from Mycobacterium tuberculosis complexed with… | x-ray diffraction | B, A | FBP, MG | 10 (best 0.67) |
| A5U1E6 | AlphaFold monomer V2.0 prediction for fructose-1,6-bisphosphatase class 2 (A5U1E6) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6AYU chain B against the predicted model A5U1E6: TM-score 0.99, RMSD 0.53 Å
- 6AYU chain B against the predicted model A5U1E6: TM-score 0.99, RMSD 0.53 Å
- 7TXB chain A against the predicted model A5U1E6: TM-score 0.99, RMSD 0.62 Å
- 6AYU chain A against the predicted model A5U1E6: TM-score 0.98, RMSD 1.13 Å
- 6AYU chain A against the predicted model A5U1E6: TM-score 0.98, RMSD 1.13 Å
- 7TXB chain B against the predicted model A5U1E6: TM-score 0.97, RMSD 1.25 Å
Elsewhere
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