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UniProt A4HXQ3

Glycogen synthase kinase 3 (A4HXQ3)

Glycogen synthase kinase 3 (UniProt A4HXQ3), EC 2.7.11.1: 2 experimental structures on GenesisL1, 3 ligands bound, 6 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A4HXQ3
Protein
Glycogen synthase kinase 3
EC
2.7.11.1
Experimental structures
2
Predicted models
0
Ligands
3
Pockets
6 · 2 records with a druggable one

Structures

2 records of A4HXQ3 in the MolNFT archive: 2 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7S6ULeishmania infantum Glycogen Synthase Kinase 3 beta bound to AZD5438x-ray diffractionAFB83 (best 0.67)
7S6VLeishmania infantum Glycogen Synthase Kinase 3 beta bound to CGP60474x-ray diffractionA8II, SO43 (best 0.67)

Ligands

  • 8II · 3-({4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl}amino)propan-1-ol · in 1 record
  • FB8 · 4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{N}-(4-methylsulfonylphenyl)pyrimidin-2-amine · in 1 record
  • SO4 · Sulfate ion · in 1 record

Elsewhere

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