UniProt A1Z1Q3
Thioredoxin 1,ADP-ribose glycohydrolase MACROD2 (A1Z1Q3)
Thioredoxin 1,ADP-ribose glycohydrolase MACROD2 (UniProt A1Z1Q3), EC 3.2.2.-, 3.5.1.-: 8 experimental structures on GenesisL1, 14 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A1Z1Q3
- Protein
- Thioredoxin 1,ADP-ribose glycohydrolase MACROD2
- EC
- 3.2.2.-, 3.5.1.-
- Experimental structures
- 8
- Predicted models
- 0
- Pockets
- 14 · 2 records with a druggable one
Structures
8 records of A1Z1Q3 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4IQY | Crystal structure of the human protein-proximal ADP-ribosyl-hydrolase MacroD2 | x-ray diffraction | A, B | — | — |
| 4IQY | Crystal structure of the human protein-proximal ADP-ribosyl-hydrolase MACROD2 | x-ray diffraction | A, B | — | — |
| 6Y4Y | The crystal structure of human MACROD2 in space group P41212 | x-ray diffraction | A, B, C, D | — | 6 (best 0.76) |
| 6Y4Y | The crystal structure of human MACROD2 in space group P41212 | x-ray diffraction | A, B, C, D | — | — |
| 6Y4Z | The crystal structure of human MACROD2 in space group P43212 | x-ray diffraction | A, B, C, D | — | 8 (best 0.76) |
| 6Y4Z | The crystal structure of human MACROD2 in space group P43212 | x-ray diffraction | A, B, C, D | — | — |
| 6Y73 | The crystal structure of human MACROD2 in space group P43 | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| A1Z1Q3 | AlphaFold monomer V2.0 prediction for ADP-ribose glycohydrolase MACROD2 (A1Z1Q3) | — | — | — |
Experiment against prediction
- 6Y4Z chain A against the predicted model P0AA25: TM-score 0.22, RMSD 3.57 Å
- 6Y4Y chain B against the predicted model P0AA25: TM-score 0.22, RMSD 3.43 Å
- 6Y4Y chain C against the predicted model P0AA25: TM-score 0.22, RMSD 3.47 Å
- 6Y4Z chain D against the predicted model P0AA25: TM-score 0.22, RMSD 3.51 Å
- 6Y4Z chain C against the predicted model P0AA25: TM-score 0.22, RMSD 3.45 Å
- 6Y4Z chain B against the predicted model P0AA25: TM-score 0.22, RMSD 3.40 Å
- 6Y4Y chain A against the predicted model P0AA25: TM-score 0.22, RMSD 3.43 Å
- 6Y4Y chain D against the predicted model P0AA25: TM-score 0.22, RMSD 3.48 Å
Elsewhere
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