UniProt A1L3X0
Elongation of very long chain fatty acids protein 7 (A1L3X0)
Elongation of very long chain fatty acids protein 7 (UniProt A1L3X0), EC 2.3.1.199: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 6 pockets. Binding sites, druggability and experiment against…
- UniProt
- A1L3X0
- Protein
- Elongation of very long chain fatty acids protein 7
- EC
- 2.3.1.199
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 6 · 1 record with a druggable one
Structures
3 records of A1L3X0 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6Y7F | Crystal structure of human ELOVL fatty acid elongase 7 (ELOVL7) | x-ray diffraction | A, B | OFN, 37X, CL | 6 (best 0.80) |
| 6Y7F | Crystal structure of human elovl fatty acid elongase 7 (ELOVL7) | x-ray diffraction | A, B | OFN, 37X, CL | — |
| A1L3X0 | AlphaFold monomer V2.0 prediction for elongation of very long chain fatty acids protein 7 (A1L3X0) | predicted | A | — | — |
Ligands
- 37X · Octyl Glucose Neopentyl Glycol · in 2 records
- CL · Chloride ion · in 2 records
- OFN · ~{S}-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 3-oxidanylideneicosanethioate · in 2 records
Experiment against prediction
- 6Y7F chain B against the predicted model A1L3X0: TM-score 0.98, RMSD 1.24 Å
- 6Y7F chain B against the predicted model A1L3X0: TM-score 0.98, RMSD 1.24 Å
- 6Y7F chain A against the predicted model A1L3X0: TM-score 0.97, RMSD 1.25 Å
- 6Y7F chain A against the predicted model A1L3X0: TM-score 0.97, RMSD 1.25 Å
Elsewhere
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