UniProt A1L0Z0
Mediator of RNA polymerase II transcription subunit 1 (A1L0Z0)
Mediator of RNA polymerase II transcription subunit 1 (UniProt A1L0Z0): 12 experimental structures and 1 predicted model on GenesisL1, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- A1L0Z0
- Protein
- Mediator of RNA polymerase II transcription subunit 1
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 16 · 1 record with a druggable one
Structures
13 records of A1L0Z0 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2ZMH | Crystal Structure of Rat Vitamin D Receptor Bound to Adamantyl Vitamin D Analogs: Structural Basis… | x-ray diffraction | C | — | 1 (best 0.35) |
| 2ZMH | Crystal structure of rat vitamin D receptor bound to adamantyl vitamin D analogs: structural basis… | x-ray diffraction | C | — | — |
| 2ZMI | Crystal Structure of Rat Vitamin D Receptor Bound to Adamantyl Vitamin D Analogs: Structural Basis… | x-ray diffraction | C | — | 1 (best 0.36) |
| 2ZMI | Crystal structure of rat vitamin D receptor bound to adamantyl vitamin D analogs: structural basis… | x-ray diffraction | C | — | — |
| 2ZMJ | Crystal Structure of Rat Vitamin D Receptor Bound to Adamantyl Vitamin D Analogs: Structural Basis… | x-ray diffraction | C | — | 1 (best 0.36) |
| 2ZMJ | Crystal structure of rat vitamin D receptor bound to adamantyl vitamin D analogs: structural basis… | x-ray diffraction | C | — | — |
| 2ZXM | A New Class of Vitamin D Receptor Ligands that Induce Structural Rearrangement of the… | x-ray diffraction | C | — | 1 (best 0.37) |
| 2ZXM | A new class of vitamin D receptor ligands that induce structural rearrangement of the… | x-ray diffraction | C | — | — |
| 2ZXN | A New Class of Vitamin D Receptor Ligands that Induce Structural Rearrangement of the… | x-ray diffraction | C | — | — |
| 2ZXN | A new class of vitamin D receptor ligands that induce structural rearrangement of the… | x-ray diffraction | C | — | — |
| 3AFR | Crystal Structure of VDR-LBD/22S-Butyl-1a,24R-dihydroxyvitamin D3 complex | x-ray diffraction | C | — | 1 (best 0.36) |
| 3AFR | Crystal structure of vdr-LBD/22S-butyl-1A,24R-dihydroxyvitamin D3 complex | x-ray diffraction | C | — | — |
| A1L0Z0 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 1 (A1L0Z0) | predicted | A | — | 11 (best 0.61) |
Experiment against prediction
- 3AFR chain C against the predicted model A1L0Z0: TM-score 0.74, RMSD 1.18 Å
- 3AFR chain C against the predicted model A1L0Z0: TM-score 0.74, RMSD 1.18 Å
- 2ZMJ chain C against the predicted model A1L0Z0: TM-score 0.66, RMSD 0.29 Å
- 2ZMJ chain C against the predicted model A1L0Z0: TM-score 0.66, RMSD 0.29 Å
- 2ZXN chain C against the predicted model A1L0Z0: TM-score 0.65, RMSD 0.46 Å
- 2ZXN chain C against the predicted model A1L0Z0: TM-score 0.65, RMSD 0.46 Å
- 2ZMH chain C against the predicted model A1L0Z0: TM-score 0.64, RMSD 0.45 Å
- 2ZMH chain C against the predicted model A1L0Z0: TM-score 0.64, RMSD 0.45 Å
- 2ZMI chain C against the predicted model A1L0Z0: TM-score 0.61, RMSD 0.57 Å
- 2ZMI chain C against the predicted model A1L0Z0: TM-score 0.61, RMSD 0.57 Å
Elsewhere
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