UniProt A1AGI6
DNA-directed RNA polymerase subunit alpha (A1AGI6)
DNA-directed RNA polymerase subunit alpha (UniProt A1AGI6), EC 2.7.7.6: 1 experimental structure and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- A1AGI6
- Protein
- DNA-directed RNA polymerase subunit alpha
- EC
- 2.7.7.6
- Experimental structures
- 1
- Predicted models
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
2 records of A1AGI6 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8F3C | Cryo-EM consensus structure of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase… | electron microscopy | G, H | — | 5 (best 0.85) |
| A1AGI6 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (A1AGI6) | predicted | A | — | 2 (best 0.45) |
Experiment against prediction
- 8F3C chain H against the predicted model A1AGI6: TM-score 0.95, RMSD 1.35 Å
- 8F3C chain G against the predicted model A1AGI6: TM-score 0.86, RMSD 2.46 Å
Elsewhere
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