UniProt A0S0A6
Endothelial nitric oxide synthase splice variant eNOS13A (A0S0A6)
Endothelial nitric oxide synthase splice variant eNOS13A (UniProt A0S0A6): 18 experimental structures on GenesisL1, 14 ligands bound, 145 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0S0A6
- Protein
- Endothelial nitric oxide synthase splice variant eNOS13A
- Experimental structures
- 18
- Predicted models
- 0
- Ligands
- 14
- Pockets
- 145 · 8 records with a druggable one
Structures
18 records of A0S0A6 in the MolNFT archive: 18 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6NH1 | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, KLY, ZN, CL, GD, H4B | 20 (best 0.85) |
| 6NH1 | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, KLY, ZN, CL, H4B, GD | — |
| 6NH2 | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, H4B, KMA, ZN, CL, GD | 20 (best 0.85) |
| 6NH2 | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, H4B, KMA, ZN, CL, GD | — |
| 6NH3 | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, KL4, ZN, CL, GD | 20 (best 0.85) |
| 6NH3 | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, KL4, ZN, CL, GD | — |
| 6NH4 | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, KLA, ZN, CL, H4B, GD | 17 (best 0.87) |
| 6NH4 | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, KLA, ZN, CL, H4B, GD | — |
| 6NH5 | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, H4B, KLD, ZN, CL, GD | 20 (best 0.85) |
| 6NH5 | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, H4B, KLD, ZN, CL, GD | — |
| 6NH6 | Structure of the human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, H4B, KL7, ZN, CL, GD | — |
| 6NH6 | Structure of the human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, H4B, KL7, ZN, CL, GD | — |
| 6NH7 | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B | HEM, KMM, ZN, GD | 9 (best 0.84) |
| 6NH7 | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B | HEM, KMM, ZN, GD | — |
| 6NH8 | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, H4B, KMS, ZN, CL, GD | 20 (best 0.85) |
| 6NH8 | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, H4B, KMS, ZN, CL, GD | — |
| 6NHF | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, H4B, KNV, ZN, CL, GD | 19 (best 0.85) |
| 6NHF | Structure of human endothelial nitric oxide synthase heme domain in complex with… | x-ray diffraction | A, B, C, D | HEM, H4B, KNV, ZN, CL, GD | — |
Ligands
- GD · Gadolinium atom · in 18 records
- HEM · Protoporphyrin IX containing Fe · in 18 records
- ZN · Zinc ion · in 18 records
- CL · Chloride ion · in 16 records
- H4B · 5,6,7,8-tetrahydrobiopterin · in 14 records
- KL4 · 6-[2-(3-fluoro-5-{2-[(2S)-pyrrolidin-2-yl]ethyl}phenyl)ethyl]-4-methylpyridin-2-amine · in 2 records
- KL7 · 6-(2-{3-[3-(dimethylamino)propyl]-2,6-difluorophenyl}ethyl)-4-methylpyridin-2-amine · in 2 records
- KLA · 6-[2-(3-fluoro-5-{2-[(2R,4S)-4-fluoropyrrolidin-2-yl]ethyl}phenyl)ethyl]-4-methylpyridin-2-amine · in 2 records
- KLD · 6-[2-(3-fluoro-5-{2-[(2R,4S)-4-fluoro-1-methylpyrrolidin-2-yl]ethyl}phenyl)ethyl]-4-methylpyridin-2-amine · in 2 records
- KLY · 6-(2-{3-fluoro-5-[3-(methylamino)prop-1-yn-1-yl]phenyl}ethyl)-4-methylpyridin-2-amine · in 2 records
- KMA · 6-[2-(3-fluoro-5-{2-[(2R)-pyrrolidin-2-yl]ethyl}phenyl)ethyl]-4-methylpyridin-2-amine · in 2 records
- KMM · 6-(2-{3-[3-(dimethylamino)propyl]-2,5,6-trifluorophenyl}ethyl)-4-methylpyridin-2-amine · in 2 records
- KMS · 6-(2-{5-[3-(dimethylamino)propyl]-2,3,4-trifluorophenyl}ethyl)-4-methylpyridin-2-amine · in 2 records
- KNV · 6-[2-(2,3-difluoro-5-{2-[(2S)-1-methylazetidin-2-yl]ethyl}phenyl)ethyl]-4-methylpyridin-2-amine · in 2 records
Elsewhere
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