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UniProt A0A8V0Z8P0

Tubulin tyrosine ligase (A0A8V0Z8P0)

Tubulin tyrosine ligase (UniProt A0A8V0Z8P0), EC 6.3.2.25: 12 experimental structures on GenesisL1, 2 ligands bound, 64 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A8V0Z8P0
Protein
Tubulin tyrosine ligase
EC
6.3.2.25
Experimental structures
12
Predicted models
0
Ligands
2
Pockets
64 · 12 records with a druggable one

Structures

12 records of A0A8V0Z8P0 in the MolNFT archive: 12 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8B7ATubulin - maytansinoid - 4 complexx-ray diffractionFACP, MG6 (best 0.81)
8B7BTubulin - maytansinoid - 6 complexx-ray diffractionFACP, MG6 (best 0.81)
8B7CTubulin-maytansinoid-12 complexx-ray diffractionFACP, MG6 (best 0.81)
8R67tubulin-cryptophycin complexx-ray diffractionFMG, ACP5 (best 0.82)
8R6OTubulin-4AZA2996 complexx-ray diffractionFACP, MG3 (best 0.88)
8RIVT2R-TTL-1-K08 complexx-ray diffractionFACP, MG5 (best 0.82)
8RIWT2R-TTL-1-L01 complexx-ray diffractionFACP, MG5 (best 0.85)
8YTXTubulin-RB3-TTL in complex with compound SI9x-ray diffractionFACP5 (best 0.80)
8YU9Tubulin-RB3-TTL in complex with compound SI10x-ray diffractionFACP5 (best 0.77)
8YUATubulin-RB3-TTL in complex with compound SI10x-ray diffractionFACP6 (best 0.83)
8ZB8Crystal structure of T2R-TTL-DPP21 complexx-ray diffractionFACP6 (best 0.80)
9FYDtubulin - cryptophycin-uD[Dab] complexx-ray diffractionFACP, MG6 (best 0.77)

Ligands

  • ACP · Phosphomethylphosphonic acid adenylate ester · in 12 records
  • MG · Magnesium ion · in 8 records

Elsewhere

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