UniProt A0A7L9RWV7

3C-like proteinase (A0A7L9RWV7)

3C-like proteinase (UniProt A0A7L9RWV7), EC 2.7.7.48, 3.4.19.12: 3 experimental structures on GenesisL1, 2 ligands bound, 8 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: A0A7L9RWV7
Protein: 3C-like proteinase
EC: 2.7.7.48, 3.4.19.12, 3.4.22.69, 3.6.4.12, 3.6.4.13
Experimental structures: 3
Predicted models: 0
Ligands: 2
Pockets: 8 · 1 record with a druggable one

Structures

3 records of A0A7L9RWV7 in the MolNFT archive: 3 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
7P2G	Identification of low micromolar SARS-CoV-2 Mpro inhibitors from hits identified by in silico…	x-ray diffraction	A	4N0	2 (best 0.50)
7P2G	Identification of low micromolar SARS-cov-2 mpro inhibitors from hits identified by in silico…	x-ray diffraction	A	4N0	—
7P35	Structure of the SARS-CoV-2 3CL protease in complex with rupintrivir	x-ray diffraction	AAA, BBB	AG7	6 (best 0.76)

Ligands

4N0 · (4~{R})-~{N}-(4-iodophenyl)-2-oxidanylidene-3,4-dihydro-1~{H}-quinoline-4-carboxamide · in 2 records
AG7 · 4-{2-(4-fluoro-benzyl)-6-methyl-5-[(5-methyl-isoxazole-3-carbonyl)-amino]-4-oxo-heptanoylamino}-5-(2-oxo-pyrrolidin-3-yl)-pentanoic acid ethyl ester · in 1 record

Elsewhere

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