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UniProt A0A6A5Q1S9

DNA replication licensing factor MCM2 (A0A6A5Q1S9)

DNA replication licensing factor MCM2 (UniProt A0A6A5Q1S9), EC 3.6.4.12: 8 experimental structures on GenesisL1, 6 ligands bound, 42 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A6A5Q1S9
Protein
DNA replication licensing factor MCM2
EC
3.6.4.12
Experimental structures
8
Predicted models
0
Ligands
6
Pockets
42 · 8 records with a druggable one

Structures

8 records of A0A6A5Q1S9 in the MolNFT archive: 8 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6HV9S. cerevisiae CMG-Pol epsilon-DNAelectron microscopy2AGS4 (best 0.88)
7PMKS. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation I)electron microscopy2ANP, MG, ZN5 (best 0.87)
7QHSS. cerevisiae CMGE nucleating origin DNA meltingelectron microscopy2ATP, ZN, MG7 (best 0.87)
7Z13S. cerevisiae CMGE dimer nucleating origin DNA meltingelectron microscopy2, aATP, ZN, MG5 (best 0.87)
8KG9Yeast replisome in state IIIelectron microscopy2ZN, ADP, MG, AGS4 (best 0.87)
8W7MYeast replisome in state Velectron microscopy2ADP, MG, ZN6 (best 0.84)
8W7SYeast replisome in state IVelectron microscopy2—6 (best 0.73)
8XGCStructure of yeast replisome associated with FACT and histone hexamer, Composite mapelectron microscopy2ZN, ADP5 (best 0.88)

Ligands

  • ZN · Zinc ion · in 6 records
  • MG · Magnesium ion · in 5 records
  • ADP · Adenosine-5'-diphosphate · in 3 records
  • AGS · Phosphothiophosphoric acid-adenylate ester · in 2 records
  • ATP · Adenosine-5'-triphosphate · in 2 records
  • ANP · Phosphoaminophosphonic acid-adenylate ester · in 1 record

Elsewhere

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