GL1X · GenesisL1 explorer

UniProt A0A6A5PUY8

DNA helicase (A0A6A5PUY8)

DNA helicase (UniProt A0A6A5PUY8), EC 3.6.4.12: 5 experimental structures on GenesisL1, 5 ligands bound, 34 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A6A5PUY8
Protein
DNA helicase
EC
3.6.4.12
Experimental structures
5
Predicted models
0
Ligands
5
Pockets
34 · 5 records with a druggable one

Structures

5 records of A0A6A5PUY8 in the MolNFT archive: 5 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6HV9S. cerevisiae CMG-Pol epsilon-DNAelectron microscopy5AGS4 (best 0.84)
7PMKS. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation I)electron microscopy5ANP, MG, ZN8 (best 0.86)
7QHSS. cerevisiae CMGE nucleating origin DNA meltingelectron microscopy5ATP, MG, ZN10 (best 0.87)
7Z13S. cerevisiae CMGE dimer nucleating origin DNA meltingelectron microscopy5, dATP, MG, ZN9 (best 0.87)
9BCXCryo-EM structure of the S. cerevisiae ORC-Cdc6-Mcm2-7-DNA complex with a fully closed Mcm2-Mcm5…electron microscopy5—3 (best 0.86)

Ligands

  • MG · Magnesium ion · in 3 records
  • ZN · Zinc ion · in 3 records
  • ATP · Adenosine-5'-triphosphate · in 2 records
  • AGS · Phosphothiophosphoric acid-adenylate ester · in 1 record
  • ANP · Phosphoaminophosphonic acid-adenylate ester · in 1 record

Elsewhere

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