UniProt A0A678ZGP6

RPA-related protein RADX peptide,Beta-2-microglobulin,MHC class I antigen chimera (A0A678ZGP6)

RPA-related protein RADX peptide,Beta-2-microglobulin,MHC class I antigen chimera (UniProt A0A678ZGP6): 3 experimental structures on GenesisL1, 29 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: A0A678ZGP6
Protein: RPA-related protein RADX peptide,Beta-2-microglobulin,MHC class I antigen…
Experimental structures: 3
Predicted models: 0
Pockets: 29 · 2 records with a druggable one

Structures

3 records of A0A678ZGP6 in the MolNFT archive: 3 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
7SR3	Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPETTDL	x-ray diffraction	A, C	—	—
7SR5	Single chain trimer HLA-A*02:01 (Y108C, A163C) with Wilms tumor protein peptide RMFPNAPYL	x-ray diffraction	A, C	—	9 (best 0.68)
7STG	Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity	x-ray diffraction	A, C, E, G, I, K, M, O, Q, S, U, W, Y, a, c, e	—	20 (best 0.69)

Experiment against prediction

7SR3 chain A against the predicted model P16213: TM-score 0.28, RMSD 1.12 Å
7STG chain Y against the predicted model P16213: TM-score 0.27, RMSD 0.67 Å
7STG chain Q against the predicted model P16213: TM-score 0.26, RMSD 0.70 Å
7STG chain M against the predicted model P16213: TM-score 0.28, RMSD 0.68 Å
7STG chain A against the predicted model P16213: TM-score 0.27, RMSD 0.68 Å
7STG chain U against the predicted model P16213: TM-score 0.29, RMSD 0.70 Å
7STG chain c against the predicted model P16213: TM-score 0.28, RMSD 0.70 Å
7STG chain K against the predicted model P16213: TM-score 0.26, RMSD 0.74 Å
7STG chain O against the predicted model P16213: TM-score 0.27, RMSD 0.73 Å
7SR3 chain C against the predicted model P16213: TM-score 0.28, RMSD 0.73 Å

Elsewhere

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