UniProt A0A4E9EZW9
Thymidylate synthase (A0A4E9EZW9)
Thymidylate synthase (UniProt A0A4E9EZW9), EC 2.1.1.45: 6 experimental structures on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A4E9EZW9
- Protein
- Thymidylate synthase
- EC
- 2.1.1.45
- Experimental structures
- 6
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 3 · 3 records with a druggable one
Structures
6 records of A0A4E9EZW9 in the MolNFT archive: 6 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DP4 | Crystal structure of wild type Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine… | x-ray diffraction | A | UMP, MTX | 1 (best 0.67) |
| 7DP4 | Crystal structure of wild type brugia malayi thymidylate synthase complexed with 2'-deoxyuridine… | x-ray diffraction | A | UMP | — |
| 7DP5 | Crystal structure of mutant V45A Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine… | x-ray diffraction | A | UMP, MTX | 1 (best 0.70) |
| 7DP5 | Crystal structure of mutant V45A brugia malayi thymidylate synthase complexed with 2'-deoxyuridine… | x-ray diffraction | A | UMP | — |
| 7DP6 | Crystal structure of mutant V45T Brugia malayi thymidylate synthase complexed with 2'-deoxyuridine… | x-ray diffraction | A | UMP | 1 (best 0.59) |
| 7DP6 | Crystal structure of mutant V45T brugia malayi thymidylate synthase complexed with 2'-deoxyuridine… | x-ray diffraction | A | UMP | — |
Ligands
Elsewhere
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