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UniProt A0A3N4BLI0

Dihydrofolate reductase (A0A3N4BLI0)

Dihydrofolate reductase (UniProt A0A3N4BLI0), EC 1.5.1.3: 2 experimental structures on GenesisL1, 4 ligands bound, 6 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A3N4BLI0
Protein
Dihydrofolate reductase
EC
1.5.1.3
Experimental structures
2
Predicted models
0
Ligands
4
Pockets
6 · 2 records with a druggable one

Structures

2 records of A0A3N4BLI0 in the MolNFT archive: 2 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8SZDCrystal structure of Yersinia pestis dihydrofolate reductase at 1.25-A resolutionx-ray diffractionASO4, CL, MG1 (best 0.51)
8SZECrystal structure of Yersinia pestis dihydrofolate reductase in complex with Trimethoprimx-ray diffractionA, BTOP, SO4, CL5 (best 0.60)

Ligands

  • CL · Chloride ion · in 2 records
  • SO4 · Sulfate ion · in 2 records
  • MG · Magnesium ion · in 1 record
  • TOP · Trimethoprim · in 1 record

Elsewhere

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