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UniProt A0A377XIN8

DNA topoisomerase 4 subunit B,DNA topoisomerase (ATP-hydrolyzing) chimera (A0A377XIN8)

DNA topoisomerase 4 subunit B,DNA topoisomerase (ATP-hydrolyzing) chimera (UniProt A0A377XIN8), EC 5.6.2.2: 2 experimental structures on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, pockets, druggability and 3D…

UniProt
A0A377XIN8
Protein
DNA topoisomerase 4 subunit B,DNA topoisomerase (ATP-hydrolyzing) chimera
EC
5.6.2.2
Experimental structures
2
Predicted models
0
Ligands
3
Pockets
20 · 1 record with a druggable one

Structures

2 records of A0A377XIN8 in the MolNFT archive: 2 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6WAAK. pneumoniae Topoisomerase IV (ParE-ParC) in complex with DNA and compound 34…x-ray diffractionB, D, F, HMG, CL, TNJ20 (best 0.87)
6WAAK. pneumoniae topoisomerase IV (pare-parc) in complex with DNA and compound 34…x-ray diffractionB, D, F, HMG, CL, TNJ—

Ligands

  • CL · Chloride ion · in 2 records
  • MG · Magnesium ion · in 2 records
  • TNJ · 7-[(1S,5R)-1-amino-3-azabicyclo[3.1.0]hexan-3-yl]-4-(aminomethyl)-1-cyclopropyl-3,6-difluoro-8-methylquinolin-2(1H)-one · in 2 records

Elsewhere

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