UniProt A0A2S1PK93
Beta-lactamase (A0A2S1PK93)
Beta-lactamase (UniProt A0A2S1PK93), EC 3.5.2.6: 18 experimental structures on GenesisL1, 12 ligands bound, 15 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A2S1PK93
- Protein
- Beta-lactamase
- EC
- 3.5.2.6
- Experimental structures
- 18
- Predicted models
- 0
- Ligands
- 12
- Pockets
- 15 · 5 records with a druggable one
Structures
18 records of A0A2S1PK93 in the MolNFT archive: 18 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6MD8 | Crystal structure of CTX-M-14 with compound 3 | x-ray diffraction | A, B | J84 | 1 (best 0.76) |
| 6MD8 | Crystal structure of ctx-M-14 with compound 3 | x-ray diffraction | A, B | J84 | — |
| 6MZ1 | CTX-M-14 Class A Beta-Lactamase in Complex with Avibactam at pH 5.3 | x-ray diffraction | A, B | NXL, PO4, K, NA | 2 (best 0.79) |
| 6MZ1 | Ctx-M-14 class a beta-lactamase in complex with avibactam at pH 5.3 | x-ray diffraction | A, B | PO4, K, NA | — |
| 6MZ2 | CTX-M-14 Class A Beta-Lactamase in Complex with Avibactam at pH 7.9 | x-ray diffraction | A, B | NXL, PO4, NA, K | 2 (best 0.73) |
| 6MZ2 | Ctx-M-14 class a beta-lactamase in complex with avibactam at pH 7.9 | x-ray diffraction | A, B | PO4, NA, K | — |
| 6OOF | CTX-M-14 Beta Lactamase with Compound 20 | x-ray diffraction | A, B | R6Z | 2 (best 0.34) |
| 6OOF | Ctx-M-14 beta lactamase with compound 20 | x-ray diffraction | A, B | R6Z | — |
| 6OOJ | CTX-M-14 Beta Lactamase with Compound 14 | x-ray diffraction | A, B | J1X | 2 (best 0.36) |
| 6OOJ | Ctx-M-14 beta lactamase with compound 14 | x-ray diffraction | A, B | J1X | — |
| 6OOK | CTX-M-14 Beta Lactamase with Compound 3 | x-ray diffraction | A, B | MZV, PO4 | 2 (best 0.34) |
| 6OOK | Ctx-M-14 beta lactamase with compound 3 | x-ray diffraction | A, B | MZV, PO4 | — |
| 6UNB | Crystal structure of CTX-M-14 in complex with temocillin | x-ray diffraction | A, B | TJ7, PO4 | — |
| 6UNB | Crystal structure of ctx-M-14 in complex with temocillin | x-ray diffraction | A, B | TJ7, PO4 | — |
| 6V7H | Structure of CTX-M-14 bound to Vaborbactam at 1.0 A | x-ray diffraction | A, B | 4D6, WXM, PO4, K | 2 (best 0.78) |
| 6V7H | Structure of ctx-M-14 bound to vaborbactam at 1.0 a | x-ray diffraction | A, B | 4D6, WXM, PO4, K | — |
| 6VHS | Crystal structure of CTX-M-14 in complex with beta-lactamase inhibitor ETX1317 | x-ray diffraction | A, B | X57, PO4 | 2 (best 0.79) |
| 6VHS | Crystal structure of ctx-M-14 in complex with beta-lactamase inhibitor ETX1317 | x-ray diffraction | A, B | X57, PO4 | — |
Ligands
- PO4 · Phosphate ion · in 12 records
- K · Potassium ion · in 6 records
- NA · Sodium ion · in 4 records
- 4D6 · Vaborbactam · in 2 records
- J1X · 3-(1H-pyrazol-1-yl)-N-[3-(1H-tetrazol-5-yl)phenyl]-5-(trifluoromethyl)benzamide · in 2 records
- J84 · 1-(2,4-dichlorophenyl)-4-(1H-tetrazol-5-yl)-1H-pyrazol-5-amine · in 2 records
- MZV · 3-(pyridin-2-yl)-N-[3-(1H-tetrazol-5-yl)phenyl]-5-(trifluoromethyl)benzamide · in 2 records
- NXL · (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide · in 2 records
- R6Z · 3-(1H-tetrazol-5-yl)-N-[3-(1H-tetrazol-5-yl)phenyl]-5-(trifluoromethyl)benzamide · in 2 records
- TJ7 · (2R,4S)-2-[(1S)-1-{[(2R)-2-carboxy-2-(thiophen-3-yl) acetyl]amino}-1-methoxy-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid · in 2 records
- WXM · 2-[(3~{R},6~{S})-2,2-bis(oxidanyl)-3-(2-thiophen-2-ylethanoylamino)-1-oxa-2-boranuidacyclohex-6-yl]ethanoic acid · in 2 records
- X57 · (2R)-({[(3R,6S)-6-carbamoyl-1-formyl-4-methyl-1,2,3,6-tetrahydropyridin-3-yl]amino}oxy)(fluoro)acetic acid · in 2 records
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.