UniProt A0A2R8Y8E0
Serine/threonine-protein kinase B-raf (A0A2R8Y8E0)
Serine/threonine-protein kinase B-raf (UniProt A0A2R8Y8E0): 2 experimental structures on GenesisL1, 1 ligand bound, 6 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A2R8Y8E0
- Protein
- Serine/threonine-protein kinase B-raf
- Experimental structures
- 2
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
2 records of A0A2R8Y8E0 in the MolNFT archive: 2 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6V34 | Crystal structure of BRAF V600E oncogenic mutant in complex with TAK-580 | x-ray diffraction | A, B | QOP | 6 (best 0.73) |
| 6V34 | Crystal structure of braf V600E oncogenic mutant in complex with tak- 580 | x-ray diffraction | A, B | QOP | — |
Ligands
- QOP · 6-amino-5-chloro-N-[(1R)-1-(5-{[5-chloro-4-(trifluoromethyl)pyridin-2-yl]carbamoyl}-1,3-thiazol-2-yl)ethyl]pyrimidine-4-carboxamide · in 2 records
Elsewhere
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