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UniProt A0A1C4HDB0

RNA-directed RNA polymerase L (A0A1C4HDB0)

RNA-directed RNA polymerase L (UniProt A0A1C4HDB0), EC 2.1.1.-, 2.7.7.48: 6 experimental structures on GenesisL1, 2 ligands bound, 103 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A1C4HDB0
Protein
RNA-directed RNA polymerase L
EC
2.1.1.-, 2.7.7.48, 2.7.7.88, 3.6.1.-
Experimental structures
6
Predicted models
0
Ligands
2
Pockets
103 · 6 records with a druggable one

Structures

6 records of A0A1C4HDB0 in the MolNFT archive: 6 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7YERThe structure of EBOV L-VP35 complexelectron microscopyAZN17 (best 0.78)
7YESThe structure of EBOV L-VP35-RNA complex (state2)electron microscopyAZN17 (best 0.75)
7YETThe structure of EBOV L-VP35 in complex with suraminelectron microscopyASVR16 (best 0.76)
8JSLThe structure of EBOV L-VP35-RNA complexelectron microscopyAZN19 (best 0.81)
8JSMThe structure of EBOV L-VP35-RNA complex (conformation 1)electron microscopyAZN17 (best 0.84)
8JSNThe structure of EBOV L-VP35-RNA complex (conformation 2)electron microscopyAZN17 (best 0.81)

Ligands

  • ZN · Zinc ion · in 5 records
  • SVR · 8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid · in 1 record

Elsewhere

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