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UniProt A0A1B0GV38

GABA(A) receptor subunit alpha-1 (A0A1B0GV38)

GABA(A) receptor subunit alpha-1 (UniProt A0A1B0GV38): 2 experimental structures on GenesisL1, 6 ligands bound, 19 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A1B0GV38
Protein
GABA(A) receptor subunit alpha-1
Experimental structures
2
Predicted models
0
Ligands
6
Pockets
19 · 1 record with a druggable one

Structures

2 records of A0A1B0GV38 in the MolNFT archive: 2 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7QNECryo-EM structure of human full-length synaptic alpha1beta3gamma2 GABA(A)R in complex with…electron microscopyA, DNAG, MAN, PIO, D10, CL, EIE19 (best 0.85)
7QNECryo-EM structure of human full-length synaptic ALPHA1BETA3GAMMA2 GABA(A)R in complex with…electron microscopyA, DNAG, MAN, PIO, D10, CL, EIE—

Ligands

  • CL · Chloride ion · in 2 records
  • D10 · Decane · in 2 records
  • EIE · Ethyl 8-[(azanylidene-$L^{4}-azanylidene)amino]-5-methyl-6-oxidanylidene-4~{H}-imidazo[1,5-A][1, 4]benzodiazepine-3-carboxylate · in 2 records
  • MAN · alpha-D-mannopyranose · in 2 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
  • PIO · [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2, 3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate · in 2 records

Elsewhere

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