UniProt A0A182M1F8
Prolyl-tRNA synthetase (A0A182M1F8)
Prolyl-tRNA synthetase (UniProt A0A182M1F8): 3 experimental structures on GenesisL1, 7 ligands bound, 34 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A182M1F8
- Protein
- Prolyl-tRNA synthetase
- Experimental structures
- 3
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 34 · 3 records with a druggable one
Structures
3 records of A0A182M1F8 in the MolNFT archive: 3 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8JE5 | Crystal Structure of Anopheles culicifacies Prolyl-tRNA Synthetase (AcPRS) in complex with Halofugi | x-ray diffraction | A, B | HFG, ZN, CL | 10 (best 0.80) |
| 8JE6 | Crystal Structure of Anopheles culicifacies Prolyl-tRNA Synthetase (AcPRS) in complex with Halofugi… | x-ray diffraction | A, B | ANP, HFG, MG, ZN | 13 (best 0.78) |
| 8JE7 | Crystal Structure of Anopheles culicifacies Prolyl-tRNA Synthetase (AcPRS) in complex with two… | x-ray diffraction | A, B | ZN, HFG, JE6, BR, CL | 11 (best 0.78) |
Ligands
- HFG · 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one · in 3 records
- ZN · Zinc ion · in 3 records
- CL · Chloride ion · in 2 records
- ANP · Phosphoaminophosphonic acid-adenylate ester · in 1 record
- BR · Bromide ion · in 1 record
- JE6 · ~{N}-[4-[(3~{S})-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-6-methyl-pyridin-2-yl]-2-phenyl-ethanamide · in 1 record
- MG · Magnesium ion · in 1 record
Elsewhere
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