UniProt A0A140NBN7
Tyrosine--tRNA ligase (A0A140NBN7)
Tyrosine--tRNA ligase (UniProt A0A140NBN7), EC 6.1.1.1: 10 experimental structures on GenesisL1, 6 ligands bound, 21 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A140NBN7
- Protein
- Tyrosine--tRNA ligase
- EC
- 6.1.1.1
- Experimental structures
- 10
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 21 · 4 records with a druggable one
Structures
10 records of A0A140NBN7 in the MolNFT archive: 10 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6HB5 | Crystal structure of E. coli tyrRS in complex with 5'-O-(N-L-tyrosyl)sulfamoyl-cytidine | x-ray diffraction | A, B | YSC, CL | 6 (best 0.68) |
| 6HB5 | Crystal structure of E. COLI tyrrs in complex with 5'-O-(N-L-tyrosyl) sulfamoyl-cytidine | x-ray diffraction | A, B | CL | — |
| 6HB6 | Crystal structure of E. coli tyrRS in complex with 5'-O-(N-L-tyrosyl)sulfamoyl-uridine | x-ray diffraction | A, B | YSU, CL | 6 (best 0.69) |
| 6HB6 | Crystal structure of E. COLI tyrrs in complex with 5'-O-(N-L-tyrosyl) sulfamoyl-uridine | x-ray diffraction | A, B | CL | — |
| 6HB7 | Crystal structure of E. coli tyrRS in complex with 5'-O-(N-L-tyrosyl)sulfamoyl-N3-methyluridine | x-ray diffraction | A, B | CL | — |
| 6HB7 | Crystal structure of E. COLI tyrrs in complex with 5'-O-(N-L-tyrosyl) sulfamoyl-N3-methyluridine | x-ray diffraction | A, B | CL | — |
| 6I5Y | Crystal structure of E. coli tyrRS in complex with 5'-O-(N-L-tyrosyl)sulfamoyl-adenosine | x-ray diffraction | A, B | YSA | 5 (best 0.69) |
| 6I5Y | Crystal structure of E. COLI tyrrs in complex with 5'-O-(N-L-tyrosyl) sulfamoyl-adenosine | x-ray diffraction | A, B | — | — |
| 7AP3 | Crystal structure of E. coli tyrosyl-tRNA synthetase in complex with TyrS7HMDDA | x-ray diffraction | A, B | RRB, NA | 4 (best 0.70) |
| 7AP3 | Crystal structure of E. COLI tyrosyl-tRNA synthetase in complex with TYRS7HMDDA | x-ray diffraction | A, B | NA | — |
Ligands
- CL · Chloride ion · in 6 records
- NA · Sodium ion · in 2 records
- RRB · [(2~{R},3~{S},4~{R},5~{R})-5-[7-azanyl-5-(hydroxymethyl)benzimidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[(2~{S})-2-azanyl-3-(4-hydroxyphenyl)propanoyl]sulfamate · in 1 record
- YSA · 5'-O-[N-(L-tyrosyl)sulfamoyl]adenosine · in 1 record
- YSC · [(2~{R},3~{S},4~{R},5~{R})-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[(2~{S})-2-azanyl-3-(4-hydroxyphenyl)propanoyl]sulfamate · in 1 record
- YSU · [(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[(2~{S})-2-azanyl-3-(4-hydroxyphenyl)propanoyl]sulfamate · in 1 record
Elsewhere
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