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UniProt A0A140E7U5

NS5 methyltransferase (A0A140E7U5)

NS5 methyltransferase (UniProt A0A140E7U5): 4 experimental structures on GenesisL1, 2 ligands bound, 26 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A140E7U5
Protein
NS5 methyltransferase
Experimental structures
4
Predicted models
0
Ligands
2
Pockets
26 · 2 records with a druggable one

Structures

4 records of A0A140E7U5 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5WZ1Crystal structure of Zika virus NS5 methyltransferase bound to S-adenosyl-L-methioninex-ray diffractionA, B, C, D, E, F, G, HSAM20 (best 0.79)
5WZ1Crystal structure of zika virus NS5 methyltransferase bound to S- adenosyl-L-methioninex-ray diffractionA, B, C, D, E, F, G, H——
5WZ2Crystal structure of Zika virus NS5 methyltransferase bound to SAM and RNA analogue (m7GpppA)x-ray diffractionA, B, CSAM, GTA6 (best 0.77)
5WZ2Crystal structure of zika virus NS5 methyltransferase bound to SAM and RNA analogue (M7GPPPA)x-ray diffractionA, B, CGTA—

Ligands

  • GTA · P1-7-methylguanosine-P3-adenosine-5',5'-triphosphate · in 2 records
  • SAM · S-adenosylmethionine · in 2 records

Elsewhere

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