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UniProt A0A0U4JN50

Hypoxanthine-guanine phosphoribosyltransferase (A0A0U4JN50)

Hypoxanthine-guanine phosphoribosyltransferase (UniProt A0A0U4JN50): 12 experimental structures on GenesisL1, 7 ligands bound, 3 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A0U4JN50
Protein
Hypoxanthine-guanine phosphoribosyltransferase
Experimental structures
12
Predicted models
0
Ligands
7
Pockets
3 · 1 record with a druggable one

Structures

12 records of A0A0U4JN50 in the MolNFT archive: 12 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5KNRE. coli HPRT in complexed with 9-[(N-phosphonoethyl-N-phosphonoethoxyethyl)-2-aminoethyl]-guaninex-ray diffractionA, B3L5, MG—
5KNRE. COLI hprt in complexed with 9-[(N-phosphonoethyl-N- phosphonoethoxyethyl)-2-aminoethyl]-guaninex-ray diffractionA, B3L5, MG—
5KNSE coli hypoxanthine guanine phosphoribosyltransferase in complexed with…x-ray diffractionA, B3L7, MG—
5KNSE COLI hypoxanthine guanine phosphoribosyltransferase in complexed with…x-ray diffractionA, B3L7, MG—
5KNTCrystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with…x-ray diffractionA, B6WB, MG—
5KNTCrystal structure of E. COLI hypoxanthine phosphoribosyltransferase in complexed with…x-ray diffractionA, B6WB, MG—
5KNUCrystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with…x-ray diffractionA, B6WA, MG3 (best 0.63)
5KNUCrystal structure of E. COLI hypoxanthine phosphoribosyltransferase in complexed with…x-ray diffractionA, B6WA, MG—
5KNVE coli hypoxanthine guanine phosphoribosyltransferase in complexed with…x-ray diffractionA, B6W9, MG—
5KNVE COLI hypoxanthine guanine phosphoribosyltransferase in complexed with…x-ray diffractionA, B6W9, MG—
5KNXCrystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with…x-ray diffractionA, B6WC, MG—
5KNXCrystal structure of E. COLI hypoxanthine phosphoribosyltransferase in complexed with…x-ray diffractionA, B6WC, MG—

Ligands

  • MG · Magnesium ion · in 12 records
  • 3L5 · (2-{[2-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl) ethyl][2-(2-phosphonoethoxy)ethyl]amino}ethyl) phosphonic acid · in 2 records
  • 3L7 · (2-{[2-(6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl](2-{[(E)-2-phosphonoethenyl]oxy}ethyl)amino}ethyl)phosphonic acid · in 2 records
  • 6W9 · 2-[2-(6-oxidanylidene-1~{H}-purin-9-yl)ethyl-(4-phosphonobutyl)amino]ethylphosphonic acid · in 2 records
  • 6WA · 3-[(4-oxidanylidene-3,5-dihydropyrrolo[3,2-d]pyrimidin-7-yl)methyl-(3-phosphonopropyl)amino]propylphosphonic acid · in 2 records
  • 6WB · 2-[[(2~{S})-2,3-bis(oxidanyl)propyl]-[2-(6-oxidanylidene-1~{H}-purin-9-yl) ethyl]amino]ethylphosphonic acid · in 2 records
  • 6WC · [2-[(6-oxidanylidene-1~{H}-purin-9-yl)methyl]-3-(phosphonomethoxy)propoxy]methylphosphonic acid · in 2 records

Elsewhere

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