UniProt A0A0T9CRX1
Polyketide synthase Pks13 (Termination polyketide synthase) (A0A0T9CRX1)
Polyketide synthase Pks13 (Termination polyketide synthase) (UniProt A0A0T9CRX1), EC 2.7.7.-: 14 experimental structures on GenesisL1, 7 ligands bound, 124 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A0T9CRX1
- Protein
- Polyketide synthase Pks13 (Termination polyketide synthase)
- EC
- 2.7.7.-
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 124 · 14 records with a druggable one
Structures
14 records of A0A0T9CRX1 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5V3W | Crystal Structure of the Apo form of Thioesterase domain of Mtb Pks13 | x-ray diffraction | A, B | 2Q5 | 10 (best 0.68) |
| 5V3W | Crystal structure of the apo form of thioesterase domain of mtb PKS13 | x-ray diffraction | A, B | 2Q5 | 10 (best 0.68) |
| 5V3X | Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor TAM1 | x-ray diffraction | A, B | I28 | 9 (best 0.72) |
| 5V3X | Crystal structure of mtb PKS13 thioesterase domain in complex with inhibitor TAM1 | x-ray diffraction | A, B | I28 | 9 (best 0.72) |
| 5V3Y | Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor TAM16 | x-ray diffraction | A, B | 5V8, SO4 | 8 (best 0.74) |
| 5V3Y | Crystal structure of mtb PKS13 thioesterase domain in complex with inhibitor TAM16 | x-ray diffraction | A, B | 5V8, SO4 | 8 (best 0.74) |
| 5V3Z | Crystal Structure of the D1607N mutant form of Thioesterase domain of Mtb Pks13 | x-ray diffraction | A, B | SO4 | 8 (best 0.74) |
| 5V3Z | Crystal structure of the D1607N mutant form of thioesterase domain of mtb PKS13 | x-ray diffraction | A, B | SO4 | 8 (best 0.74) |
| 5V40 | Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor TAM6 | x-ray diffraction | A, B | JS1 | 9 (best 0.70) |
| 5V40 | Crystal structure of mtb PKS13 thioesterase domain in complex with inhibitor TAM6 | x-ray diffraction | A, B | JS1 | 9 (best 0.70) |
| 5V41 | Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor TAM5 | x-ray diffraction | A, B | J24 | 10 (best 0.71) |
| 5V41 | Crystal structure of mtb PKS13 thioesterase domain in complex with inhibitor TAM5 | x-ray diffraction | A, B | J24 | 10 (best 0.71) |
| 5V42 | Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor TAM3 | x-ray diffraction | A, B | I66 | 8 (best 0.73) |
| 5V42 | Crystal structure of mtb PKS13 thioesterase domain in complex with inhibitor TAM3 | x-ray diffraction | A, B | I66 | 8 (best 0.73) |
Ligands
- SO4 · Sulfate ion · in 4 records
- 2Q5 · (2R)-2-{[(2R)-2-{[(2S)-2-{[(2R)-2-hydroxypropyl]oxy}propyl]oxy}propyl]oxy}propan-1-ol · in 2 records
- 5V8 · 2-(4-hydroxyphenyl)-~{N}-methyl-5-oxidanyl-4-(piperidin-1-ylmethyl)-1-benzofuran-3-carboxamide · in 2 records
- I28 · ethyl 5-hydroxy-4-[(4-methylpiperidin-1-yl)methyl]-2-phenyl-1-benzofuran-3-carboxylate · in 2 records
- I66 · ethyl 5-hydroxy-2-phenyl-4-(pyrrolidin-1-ylmethyl)-1-benzofuran-3-carboxylate · in 2 records
- J24 · ethyl 5-hydroxy-4-(morpholin-4-ylmethyl)-2-phenyl-1-benzofuran-3-carboxylate · in 2 records
- JS1 · ethyl 4-[(dimethylamino)methyl]-5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate · in 2 records
Elsewhere
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