UniProt A0A0E8VY41
DNA topoisomerase 1 (A0A0E8VY41)
DNA topoisomerase 1 (UniProt A0A0E8VY41), EC 5.6.2.1, 5.99.1.2: 6 experimental structures on GenesisL1, 2 ligands bound, 33 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A0E8VY41
- Protein
- DNA topoisomerase 1
- EC
- 5.6.2.1, 5.99.1.2
- Experimental structures
- 6
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 33 · 4 records with a druggable one
Structures
6 records of A0A0E8VY41 in the MolNFT archive: 6 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UJ1 | Crystal structure of Mycobacterium tuberculosis Topoisomerase I at 2.15A resolution limit | x-ray diffraction | A | SO4 | 4 (best 0.69) |
| 5UJ1 | Crystal structure of mycobacterium tuberculosis topoisomerase I at 2.15A resolution limit | x-ray diffraction | A | SO4 | — |
| 5UJY | The structure of Mycobacterium tuberculosis topoisomerase I from the 2nd crystal form | x-ray diffraction | A, B | — | 15 (best 0.70) |
| 5UJY | The structure of mycobacterium tuberculosis topoisomerase I from the 2ND crystal form | x-ray diffraction | A, B | — | — |
| 8CZQ | The crystal structure of MtbTOP1 in complex with both G- and T-segments | x-ray diffraction | A | PO4 | 10 (best 0.76) |
| 8TFG | 1.88A crystal structure of mycobacterium tuberculosis topoisomerase I | x-ray diffraction | A | — | 4 (best 0.71) |
Ligands
Elsewhere
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