UniProt A0A0A7Y424
Metallo-beta-lactamase NDM-1 (A0A0A7Y424)
Metallo-beta-lactamase NDM-1 (UniProt A0A0A7Y424): 9 experimental structures on GenesisL1, 8 ligands bound, 3 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A0A7Y424
- Protein
- Metallo-beta-lactamase NDM-1
- Experimental structures
- 9
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 3 · 1 record with a druggable one
Structures
9 records of A0A0A7Y424 in the MolNFT archive: 9 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5YPI | Crystal structure of ndm-1 bound to hydrolyzed imipenem representing an EI1 complex | x-ray diffraction | A, B, C, D, E, F, G, H | ZN, 8YF, SO4, CL | — |
| 5YPK | Crystal structure of NDM-1 bound to hydrolyzed imipenem representing an EI2 complex | x-ray diffraction | A, B, C, D, E, F, G, H | ZN, HIW, SO4, NA, CL | — |
| 5YPK | Crystal structure of ndm-1 bound to hydrolyzed imipenem representing an EI2 complex | x-ray diffraction | A, B, C, D, E, F, G, H | ZN, HIW, SO4, NA, CL | — |
| 5YPL | Crystal structure of NDM-1 bound to hydrolyzed imipenem representing an EP complex | x-ray diffraction | A, B | ZN, HIW, SO4, CL | — |
| 5YPL | Crystal structure of ndm-1 bound to hydrolyzed imipenem representing an ep complex | x-ray diffraction | A, B | ZN, HIW, SO4, CL | — |
| 5YPM | Crystal structure of NDM-1 bound to hydrolyzed meropenem representing an EI1 complex | x-ray diffraction | A, B, C, D, E, F, G, H | ZN, SO4 | — |
| 5YPM | Crystal structure of ndm-1 bound to hydrolyzed meropenem representing an EI1 complex | x-ray diffraction | A, B, C, D, E, F, G, H | ZN, SO4 | — |
| 5YPN | Crystal structure of ndm-1 bound to hydrolyzed meropenem representing an EI2 complex | x-ray diffraction | A, B | ZN, LMP, SO4 | — |
| 7VQJ | Crystal structure of NDM-1 in complex with hydrolyzed 1u. | x-ray diffraction | A, B | ZN, 7T6 | 3 (best 0.79) |
Ligands
- ZN · Zinc ion · in 9 records
- SO4 · Sulfate ion · in 8 records
- CL · Chloride ion · in 5 records
- HIW · (2R,4S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[(2-{[(Z)-iminomethyl]amino}ethyl)sulfanyl]-3,4-dihydro-2H-pyrrole-5-carboxylic acid · in 4 records
- NA · Sodium ion · in 2 records
- 7T6 · (2R)-2-[(1S)-1-methoxy-2-oxidanyl-2-oxidanylidene-ethyl]-5-methylidene-2H-1,3-thiazine-4-carboxylic acid · in 1 record
- 8YF · (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole-5-carboxylic acid · in 1 record
- LMP · (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid · in 1 record
Elsewhere
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