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UniProt A0A087X2I1

26S proteasome regulatory subunit 10B (A0A087X2I1)

26S proteasome regulatory subunit 10B (UniProt A0A087X2I1): 37 experimental structures on GenesisL1, 4 ligands bound, 164 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A087X2I1
Protein
26S proteasome regulatory subunit 10B
Experimental structures
37
Predicted models
0
Ligands
4
Pockets
164 · 37 records with a druggable one

Structures

37 records of A0A087X2I1 in the MolNFT archive: 37 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5T0GStructural basis for dynamic regulation of the human 26S proteasomeelectron microscopyEATP7 (best 0.88)
5T0GStructural basis for dynamic regulation of the human 26S proteasomeelectron microscopyEATP7 (best 0.88)
5T0HStructural basis for dynamic regulation of the human 26S proteasomeelectron microscopyEADP5 (best 0.82)
5T0HStructural basis for dynamic regulation of the human 26S proteasomeelectron microscopyEADP5 (best 0.82)
5T0IStructural basis for dynamic regulation of the human 26S proteasomeelectron microscopyEATP6 (best 0.86)
5T0IStructural basis for dynamic regulation of the human 26S proteasomeelectron microscopyEATP6 (best 0.86)
5T0JStructural basis for dynamic regulation of the human 26S proteasomeelectron microscopyEATP4 (best 0.86)
5T0JStructural basis for dynamic regulation of the human 26S proteasomeelectron microscopyEATP4 (best 0.86)
6MSBCryo-EM structures and dynamics of substrate-engaged human 26S proteasomeelectron microscopyEATP, MG5 (best 0.83)
6MSDCryo-EM structures and dynamics of substrate-engaged human 26S proteasomeelectron microscopyEATP, MG4 (best 0.84)
6MSECryo-EM structures and dynamics of substrate-engaged human 26S proteasomeelectron microscopyEATP, MG, ADP4 (best 0.84)
6MSGCryo-EM structures and dynamics of substrate-engaged human 26S proteasomeelectron microscopyEATP, MG4 (best 0.83)
6MSHCryo-EM structures and dynamics of substrate-engaged human 26S proteasomeelectron microscopyEATP5 (best 0.85)
6MSJCryo-EM structures and dynamics of substrate-engaged human 26S proteasomeelectron microscopyEATP, MG, ADP6 (best 0.86)
6MSKCryo-EM structures and dynamics of substrate-engaged human 26S proteasomeelectron microscopyE—3 (best 0.85)
6WJDSA-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin…electron microscopyEAGS, MG4 (best 0.89)
7QXNProteasome-ZFAND5 Complex Z+A stateelectron microscopyEATP, MG4 (best 0.83)
7QXPProteasome-ZFAND5 Complex Z+B stateelectron microscopyEATP, MG5 (best 0.82)
7QXUProteasome-ZFAND5 Complex Z+C stateelectron microscopyEATP, MG5 (best 0.83)
7QXWProteasome-ZFAND5 Complex Z+D stateelectron microscopyEATP, MG, ADP3 (best 0.83)
7QXXProteasome-ZFAND5 Complex Z+E stateelectron microscopyEATP, MG4 (best 0.83)
7QY7Proteasome-ZFAND5 Complex Z-A stateelectron microscopyEATP3 (best 0.88)
7QYAProteasome-ZFAND5 Complex Z-B stateelectron microscopyEATP5 (best 0.85)
7QYBProteasome-ZFAND5 Complex Z-C stateelectron microscopyE—3 (best 0.82)
7W37Structure of USP14-bound human 26S proteasome in state EA1_UBLelectron microscopyEATP, MG5 (best 0.81)
7W38Structure of USP14-bound human 26S proteasome in state EA2.0_UBLelectron microscopyEATP, MG6 (best 0.83)
7W39Structure of USP14-bound human 26S proteasome in state EA2.1_UBLelectron microscopyEATP, MG4 (best 0.85)
7W3AStructure of USP14-bound human 26S proteasome in substrate-engaged state ED4_USP14electron microscopyEATP3 (best 0.86)
7W3BStructure of USP14-bound human 26S proteasome in substrate-engaged state ED5_USP14electron microscopyEATP4 (best 0.86)
7W3CStructure of USP14-bound human 26S proteasome in substrate-engaged state ED0_USP14electron microscopyEATP, ADP3 (best 0.85)
7W3FStructure of USP14-bound human 26S proteasome in substrate-engaged state ED1_USP14electron microscopyEATP, ADP5 (best 0.87)
7W3GStructure of USP14-bound human 26S proteasome in substrate-engaged state ED2.0_USP14electron microscopyEADP3 (best 0.87)
7W3HStructure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14electron microscopyE—4 (best 0.81)
7W3IStructure of USP14-bound human 26S proteasome in substrate-inhibited state SB_USP14electron microscopyEATP3 (best 0.85)
7W3JStructure of USP14-bound human 26S proteasome in substrate-inhibited state SC_USP14electron microscopyEATP4 (best 0.85)
7W3KStructure of USP14-bound human 26S proteasome in substrate-inhibited state SD4_USP14electron microscopyEATP5 (best 0.85)
7W3MStructure of USP14-bound human 26S proteasome in substrate-inhibited state SD5_USP14electron microscopyEATP4 (best 0.85)

Ligands

  • ATP · Adenosine-5'-triphosphate · in 30 records
  • MG · Magnesium ion · in 14 records
  • ADP · Adenosine-5'-diphosphate · in 8 records
  • AGS · Phosphothiophosphoric acid-adenylate ester · in 1 record

Elsewhere

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