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UniProt A0A076Q3N8

Reverse transcriptase P51 subunit (A0A076Q3N8)

Reverse transcriptase P51 subunit (UniProt A0A076Q3N8), EC 2.7.7.49, 3.1.13.2: 12 experimental structures on GenesisL1, 5 ligands bound, 74 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A076Q3N8
Protein
Reverse transcriptase P51 subunit
EC
2.7.7.49, 3.1.13.2, 3.1.26.13
Experimental structures
12
Predicted models
0
Ligands
5
Pockets
74 · 5 records with a druggable one

Structures

12 records of A0A076Q3N8 in the MolNFT archive: 12 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6BHJStructure of HIV-1 Reverse Transcriptase Bound to a 38-mer Hairpin Template-Primer RNA-DNA Aptamerx-ray diffractionA, B, C, DGLC, FRU, MG, SO420 (best 0.82)
6BHJStructure of HIV-1 reverse transcriptase bound to a 38-mer hairpin template-primer RNA-DNA aptamerx-ray diffractionA, B, C, DGLC, FRU, MG, SO4—
6BSGStructure of HIV-1 RT complexed with RNA/DNA hybrid in an RNA hydrolysis-off modex-ray diffractionB—14 (best 0.81)
6BSGStructure of HIV-1 rt complexed with RNA/DNA hybrid in an RNA hydrolysis-off modex-ray diffractionB——
6BSHStructure of HIV-1 RT complexed with RNA/DNA hybrid in the RNA hydrolysis modex-ray diffractionBEFZ—
6BSHStructure of HIV-1 rt complexed with RNA/DNA hybrid in the RNA hydrolysis modex-ray diffractionBEFZ—
6BSIStructure of HIV-1 RT complexed with an RNA/DNA hybrid containing the polypurine-tract sequencex-ray diffractionB—16 (best 0.82)
6BSIStructure of HIV-1 rt complexed with an RNA/DNA hybrid containing the polypurine-tract sequencex-ray diffractionB——
6BSJStructure of HIV-1 RT complexed with an RNA/DNA hybrid sequence non-preferred for RNA hydrolysisx-ray diffractionB—15 (best 0.83)
6BSJStructure of HIV-1 rt complexed with an RNA/DNA hybrid sequence non- preferred for RNA hydrolysisx-ray diffractionB——
6VUGDiabody bound to a Reverse Transcriptase Aptamer Complexx-ray diffractionBSO49 (best 0.84)
6VUGDiabody bound to a reverse transcriptase aptamer complexx-ray diffractionBSO4—

Ligands

  • SO4 · Sulfate ion · in 4 records
  • EFZ · (-)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1, 4-dihydro-2H-3,1-benzoxazin-2-one · in 2 records
  • FRU · beta-D-fructofuranose · in 2 records
  • GLC · alpha-D-glucopyranose · in 2 records
  • MG · Magnesium ion · in 2 records

Elsewhere

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