UniProt A0A075B6T6
T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5 (A0A075B6T6)
T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5 (UniProt A0A075B6T6): 11 experimental structures and 1 predicted model on GenesisL1, 47 pockets. Binding sites, druggability and experiment against…
- UniProt
- A0A075B6T6
- Protein
- T cell receptor alpha variable 12-2,T cell receptor alpha chain MC.7.G5
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 47 · 5 records with a druggable one
Structures
12 records of A0A075B6T6 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5E9D | RD-1 Mart-1 High bound to Mart-1 decameric peptide (ELA) in complex with HLA-A2 | x-ray diffraction | D, I | — | 10 (best 0.69) |
| 5E9D | Rd-1 mart-1 high bound to mart-1 decameric peptide (ela) in complex with HLA-A2 | x-ray diffraction | D, I | — | — |
| 5NHT | human 199.54-16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2 | x-ray diffraction | A | — | — |
| 5NHT | Human 199.54-16 TCR in complex with melan-A/MART-1 (26-35) peptide and HLA-A2 | x-ray diffraction | A | — | — |
| 5NQK | human 199.16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2 | x-ray diffraction | A | — | — |
| 5NQK | Human 199.16 TCR in complex with melan-A/MART-1 (26-35) peptide and HLA-A2 | x-ray diffraction | A | — | — |
| 6DKP | The complex among DMF5(alpha-D26Y, alpha-Y50A,beta-L98W) TCR, human Class I MHC HLA-A2 and… | x-ray diffraction | D | — | 3 (best 0.75) |
| 6DKP | The complex among DMF5(ALPHA-D26Y, alpha-Y50A,BETA-L98W) TCR, human class I MHC HLA-A2 and… | x-ray diffraction | D | — | — |
| 8RLT | TCR in complex with HLA-E*01:03 bound to HBV envelope 371-379 index peptide | x-ray diffraction | D, I | — | 12 (best 0.75) |
| 8RLU | TCR in complex with HLA-E*01:03 bound to HBV envelope 371-379 S3N peptide | x-ray diffraction | D, I | — | 9 (best 0.74) |
| 8RLV | TCR in complex with HLA-E*01:03 bound to HBV envelope 371-379 L6I peptide | x-ray diffraction | D, I | — | 13 (best 0.75) |
| A0A075B6T6 | AlphaFold monomer V2.0 prediction for T cell receptor alpha variable 12-2 (A0A075B6T6) | predicted | — | — |
Experiment against prediction
- 8RLT chain D against the predicted model P0DTU3: TM-score 0.89, RMSD 2.03 Å
- 8RLU chain D against the predicted model P0DTU3: TM-score 0.89, RMSD 2.09 Å
- 8RLV chain D against the predicted model P0DTU3: TM-score 0.89, RMSD 2.05 Å
- 8RLV chain I against the predicted model P0DTU3: TM-score 0.89, RMSD 2.04 Å
- 8RLU chain I against the predicted model P0DTU3: TM-score 0.88, RMSD 2.10 Å
- 8RLT chain I against the predicted model P0DTU3: TM-score 0.88, RMSD 2.07 Å
- 6DKP chain D against the predicted model P01848: TM-score 0.41, RMSD 1.18 Å
- 6DKP chain D against the predicted model P01848: TM-score 0.41, RMSD 1.18 Å
Elsewhere
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