UniProt A0A066Q637
4-hydroxy-tetrahydrodipicolinate synthase (A0A066Q637)
4-hydroxy-tetrahydrodipicolinate synthase (UniProt A0A066Q637), EC 4.3.3.7: 22 experimental structures on GenesisL1, 3 ligands bound, 50 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A066Q637
- Protein
- 4-hydroxy-tetrahydrodipicolinate synthase
- EC
- 4.3.3.7
- Experimental structures
- 22
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 50 · 11 records with a druggable one
Structures
22 records of A0A066Q637 in the MolNFT archive: 22 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6NVA | Crystal structure of Escherichia coli dihydrodipicolinate synthase and propionate covalently bound… | x-ray diffraction | A, B, C, D, E, F, G, H | NA | 20 (best 0.77) |
| 6NVA | Crystal structure of escherichia COLI dihydrodipicolinate synthase and propionate covalently bound… | x-ray diffraction | A, B, C, D, E, F, G, H | NA | — |
| 7JZ7 | Dihydrodipicolinate synthase mutant S48F | x-ray diffraction | A, B | K | 3 (best 0.60) |
| 7JZ7 | Dihydrodipicolinate synthase mutant S48F | x-ray diffraction | A, B | K | — |
| 7JZ8 | Dihydrodipicolinate synthase mutant S48F with lysine in the allosteric site | x-ray diffraction | A, B | K, LYS | 3 (best 0.64) |
| 7JZ8 | Dihydrodipicolinate synthase mutant S48F with lysine in the allosteric site | x-ray diffraction | A, B | K | — |
| 7JZ9 | Dihydrodipicolinate synthase S48F with pyruvate and succinic semi-aldehyde | x-ray diffraction | A, B | K | 3 (best 0.64) |
| 7JZ9 | Dihydrodipicolinate synthase S48F with pyruvate and succinic semi- aldehyde | x-ray diffraction | A, B | K | — |
| 7JZA | Dihydrodipicolinate synthase S48F mutant with lysine in the allosteric site, and pyruvate and… | x-ray diffraction | A, B | K, LYS | 3 (best 0.63) |
| 7JZA | Dihydrodipicolinate synthase S48F mutant with lysine in the allosteric site, and pyruvate and… | x-ray diffraction | A, B | K | — |
| 7JZB | Dihydrodipicolinate synthase S48W with lysine in the allosteric site, and pyruvate and succinic… | x-ray diffraction | A, B | K, LYS | 3 (best 0.70) |
| 7JZB | Dihydrodipicolinate synthase S48W with lysine in the allosteric site, and pyruvate and succinic… | x-ray diffraction | A, B | K | — |
| 7JZC | Dihydrodipicolinate synthase S48W mutant with lysine in the allosteric site, and pyruvate in the… | x-ray diffraction | A, B | K | 3 (best 0.71) |
| 7JZC | Dihydrodipicolinate synthase S48W mutant with lysine in the allosteric site, and pyruvate in the… | x-ray diffraction | A, B | K | — |
| 7JZD | Dihydrodipicolinate synthase mutation S48W with Lysine in the allosteric site | x-ray diffraction | A, B | K | 3 (best 0.72) |
| 7JZD | Dihydrodipicolinate synthase mutation S48W with lysine in the allosteric site | x-ray diffraction | A, B | K | — |
| 7JZE | Dihydrodipicolinate synthase mutant S48W | x-ray diffraction | A, B | K | 3 (best 0.73) |
| 7JZE | Dihydrodipicolinate synthase mutant S48W with lysine in the allosteric site | x-ray diffraction | A, B | K | — |
| 7JZF | Dihydrodipicolinate synthase mutant S48F with pyruvate in the catalytic site | x-ray diffraction | A, B | K | 3 (best 0.67) |
| 7JZF | Dihydrodipicolinate synthase mutant S48F with pyruvate in the catalytic site | x-ray diffraction | A, B | K | — |
| 7JZG | Dihydrodipicolinate synthase mutant S48F with lysine in the allosteric site and pyruvate in the… | x-ray diffraction | A, B | K, LYS | 3 (best 0.63) |
| 7JZG | Dihydrodipicolinate synthase mutant S48F with lysine in the allosteric site and pyruvate in the… | x-ray diffraction | A, B | K | — |
Ligands
Elsewhere
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