UniProt A0A024X378
Lysine--tRNA ligase (A0A024X378)
Lysine--tRNA ligase (UniProt A0A024X378), EC 6.1.1.6: 4 experimental structures on GenesisL1, 5 ligands bound, 46 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A024X378
- Protein
- Lysine--tRNA ligase
- EC
- 6.1.1.6
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 46 · 4 records with a druggable one
Structures
4 records of A0A024X378 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8K9S | Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 1 (ADKI1) | x-ray diffraction | A, B | LYS, JRU | 10 (best 0.83) |
| 8K9U | Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 2 (ADKI2) | x-ray diffraction | A, B | LYS, JSL | 11 (best 0.80) |
| 8K9W | Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 4 (ADKI4) | x-ray diffraction | A, B | JTR | 12 (best 0.83) |
| 8K9X | Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 5 (ADKI5) | x-ray diffraction | A, B | JUA | 13 (best 0.82) |
Ligands
- LYS · Lysine · in 2 records
- JRU · methyl 4-methoxy-3-[[4-[(2-propan-2-ylsulfonylphenyl)amino]-1,3,5-triazin-2-yl]amino]benzoate · in 1 record
- JSL · ~{N}4-(2,4-dimethoxyphenyl)-~{N}2-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine · in 1 record
- JTR · ~{N}2-(2-methoxyphenyl)-~{N}4-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine · in 1 record
- JUA · (2~{S})-2,6-bis(azanyl)-~{N}-[3-[2-[[4-[(2,5-dimethoxyphenyl)amino]-1,3,5-triazin-2-yl]amino]phenyl]sulfonylpropyl]hexanamide · in 1 record
Elsewhere
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