UniProt A0A024V0B1
Probable M17 family aminopeptidase (A0A024V0B1)
Probable M17 family aminopeptidase (UniProt A0A024V0B1), EC 3.4.11.1: 9 experimental structures on GenesisL1, 6 ligands bound, 60 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A024V0B1
- Protein
- Probable M17 family aminopeptidase
- EC
- 3.4.11.1
- Experimental structures
- 9
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 60 · 3 records with a druggable one
Structures
9 records of A0A024V0B1 in the MolNFT archive: 9 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4ZX8 | X-ray crystal structure of pfa-M17 in complex with hydroxamic acid- based inhibitor 9B | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 4ZX9 | X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10b | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | 4TK, ZN, CO3, SO4 | 20 (best 0.77) |
| 4ZX9 | X-ray crystal structure of pfa-M17 in complex with hydroxamic acid- based inhibitor 10B | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 4ZY0 | X-ray crystal structure of pfa-M17 in complex with hydroxamic acid- based inhibitor 10Q | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 4ZY1 | X-ray crystal structure of pfa-M17 in complex with hydroxamic acid- based inhibitor 10R | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 4ZYQ | X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10s | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | 4U6, ZN, CO3, SO4 | 20 (best 0.76) |
| 4ZYQ | X-ray crystal structure of pfa-M17 in complex with hydroxamic acid- based inhibitor 10S | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 5CBM | Crystal structure of PfA-M17 with virtual ligand inhibitor | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | CO3, ZN, 4ZN, SO4 | 20 (best 0.74) |
| 5CBM | Crystal structure of pfa-M17 with virtual ligand inhibitor | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
Ligands
- CO3 · Carbonate ion · in 3 records
- SO4 · Sulfate ion · in 3 records
- ZN · Zinc ion · in 3 records
- 4TK · N-[(1R)-1-(4-bromophenyl)-2-(hydroxyamino)-2-oxoethyl]-2,2-dimethylpropanamide · in 1 record
- 4U6 · N-{(1R)-2-(hydroxyamino)-1-[3'-(N'-hydroxycarbamimidoyl)biphenyl-4-yl]-2-oxoethyl}-2,2-dimethylpropanamide · in 1 record
- 4ZN · (2S)-2-{[(R)-[(R)-amino(phenyl)methyl](hydroxy)phosphoryl]methyl}-4-methylpentanoic acid · in 1 record
Elsewhere
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