GL1X · GenesisL1 explorer

Ligand · ZPG

ZPG · (2S,5R,8R,11S,14S,17S,21R)-5,8,11,14,17-pentamethyl-4,7,10,13,16,19-hexaoxadocosane-2,21-diol

ZPG, (2S,5R,8R,11S,14S,17S,21R)-5,8,11,14,17-pentamethyl-4,7,10,13,16,19-hexaoxadocosane-2,21-diol (C21 H44 O8, 424.6 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues…

Component
ZPG
Formula
C21 H44 O8
Class
ligand
Structures
8
PDB entries
4

Binding sites

ZPG in 8 structures; the first of them:

  • 2H2I · The Structural basis of Sirtuin Substrate Affinity · ZPG A1001 · binds PHE33, ARG34, PHE48, PHE63, ILE68, GLN98, ILE100, HIS116 and 6 more
  • 3Q6I · Crystal structure of FabG4 and coenzyme binary complex · ZPG A455 · binds ILE348, ASN354, THR405, VAL408, GLY409, ILE452, LEU26, MET451
  • 3V1U · Crystal structure of a beta-ketoacyl reductase FabG4 from Mycobacterium tuberculosis… · ZPG A503 · binds ASP199, GLU338, ALA379, ALA380, LYS381, GLY382
  • 4FW8 · Crystal structure of FABG4 complexed with Coenzyme NADH · ZPG A502 · binds ILE348, ASN354, THR405, GLY409, ILE452, LEU26, MET451
  • 2H2I · The structural basis of sirtuin substrate affinity · ZPG A1001 · binds PHE33, ARG34, PHE48, PHE63, ILE68, GLN98, ILE100, HIS116 and 6 more
  • 3Q6I · Crystal structure of FABG4 and coenzyme binary complex · ZPG A455 · binds ILE348, ASN354, THR405, VAL408, GLY409, ILE452, LEU26, MET451
  • 3V1U · Crystal structure of a beta-ketoacyl reductase FABG4 from mycobacterium tuberculosis… · ZPG A503 · binds ASP199, GLU338, ALA379, ALA380, LYS381, GLY382
  • 4FW8 · Crystal structure of FABG4 complexed with coenzyme NADH · ZPG A502 · binds ILE348, ASN354, THR405, GLY409, ILE452, LEU26, MET451

Residues it binds most

ILE 6, PHE 2, GLY 6, LEU 6, ALA 2, ASN 4, MET 4, THR 4, VAL 4, ARG 2 (residue and the binding sites it lines).

Found with

  • NAD · Nicotinamide-adenine-dinucleotide
  • HXC · Hexanoyl-coenzyme A
  • NAI · 1,4-dihydronicotinamide adenine dinucleotide
  • ZN · Zinc ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.