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Ligand · ZMJ

ZMJ · N-[3-(2-methyl-1-oxo-1,2-dihydroisoquinolin-4-yl) phenyl]ethanesulfonamide

ZMJ, N-[3-(2-methyl-1-oxo-1,2-dihydroisoquinolin-4-yl) phenyl]ethanesulfonamide (C18 H18 N2 O3 S, 342.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å…

Component
ZMJ
Formula
C18 H18 N2 O3 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

ZMJ in 4 structures; the first of them:

  • 7MRA · Crystal structure of the first bromodomain (BD1) of human BRD4 bound to NC-II-259 · ZMJ A201 · binds TRP81, PRO82, PHE83, GLN84, GLN85, PRO86, VAL87, ASP88 and 8 more
  • 7MRH · Crystal structure of the first bromodomain (BD1) of human BRDT bound to NC-II-259 · ZMJ A201 · binds TRP50, PRO51, PHE52, GLN53, ARG54, PRO55, VAL56, ASP57 and 7 more
  • 7MRA · Crystal structure of the first bromodomain (BD1) of human BRD4 bound to nc-II-259 · ZMJ A201 · binds TRP81, PRO82, PHE83, GLN85, PRO86, VAL87, ASP88, LYS91 and 4 more
  • 7MRH · Crystal structure of the first bromodomain (BD1) of human brdt bound to nc-II-259 · ZMJ A201 · binds TRP50, PRO51, PHE52, ARG54, PRO55, VAL56, ASP57, LYS60 and 5 more

Residues it binds most

LEU 6, PRO 6, ASN 6, ASP 6, ILE 6, LYS 6, PHE 6, TRP 6, VAL 6, CYS 5 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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