Ligand · ZM4

ZM4 · 3'-[(2S)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-4'-methyl[1,1'-biphenyl]-4-carboxamide

ZM4, 3'-[(2S)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-4'-methyl[1,1'-biphenyl]-4-carboxamide (C24 H25 N5 O, 399.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component: ZM4
Formula: C24 H25 N5 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

ZM4 in 2 structures; the first of them:

7MQP · E. coli dihydrofolate reductase complexed with… · ZM4 A201 · binds ILE5, ALA6, ALA7, MET16, GLU17, ASN18, ASP27, LEU28 and 10 more
7MQP · E. COLI dihydrofolate reductase complexed with 4'-chloro-3'-(4-(2,4… · ZM4 A201 · binds ILE5, ALA6, ALA7, MET16, GLU17, ASN18, ASP27, LEU28 and 9 more

Residues it binds most

ILE 2, ALA 2, LEU 2, THR 2, ASN 2, ASP 2, GLU 2, LYS 2, MET 2, PHE 2 (residue and the binding sites it lines).

Found with

SO4 · Sulfate ion

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